Preeclampsia in 2018: Revisiting Concepts, Physiopathology, and Prediction

Preeclampsia currently remains one of the leading causes of death and severe maternal morbidity. Although its prevalence is still underestimated in some places due to underreporting, preeclampsia is a disease that health professionals need to know how to deal with and take action. For this reason, t...

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Main Authors: J. Mayrink, M. L. Costa, J. G. Cecatti
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2018/6268276
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author J. Mayrink
M. L. Costa
J. G. Cecatti
author_facet J. Mayrink
M. L. Costa
J. G. Cecatti
author_sort J. Mayrink
collection DOAJ
description Preeclampsia currently remains one of the leading causes of death and severe maternal morbidity. Although its prevalence is still underestimated in some places due to underreporting, preeclampsia is a disease that health professionals need to know how to deal with and take action. For this reason, the studies about the theme remain along with the advances in their understanding that often implies improvement and change of concepts and conducts. The complexity of its etiology is a challenge and requires further studies for its full understanding. Apparently, poor adaptation of the maternal organism to the conceptus, marked by the nonoccurrence of changes in the uterine spiral arteries, determines a series of systemic repercussions that compound the various forms of preeclampsia presentation. In recent years, the use of acetylsalicylic acid to prevent cases of early onset of the disease has been consolidated and, alongside, studies have advanced the development of accessible and effective methods of identifying women at risk of preeclampsia. The aim of this review is to discuss updates on the occurrence, concept, pathophysiology, repercussion, prevention, and prediction of preeclampsia.
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spelling doaj-art-ca22dd68c9fe45d78d05f63f87d4a40f2025-02-03T06:14:12ZengWileyThe Scientific World Journal2356-61401537-744X2018-01-01201810.1155/2018/62682766268276Preeclampsia in 2018: Revisiting Concepts, Physiopathology, and PredictionJ. Mayrink0M. L. Costa1J. G. Cecatti2Obstetric Unit, Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas, Campinas, BrazilObstetric Unit, Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas, Campinas, BrazilObstetric Unit, Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas, Campinas, BrazilPreeclampsia currently remains one of the leading causes of death and severe maternal morbidity. Although its prevalence is still underestimated in some places due to underreporting, preeclampsia is a disease that health professionals need to know how to deal with and take action. For this reason, the studies about the theme remain along with the advances in their understanding that often implies improvement and change of concepts and conducts. The complexity of its etiology is a challenge and requires further studies for its full understanding. Apparently, poor adaptation of the maternal organism to the conceptus, marked by the nonoccurrence of changes in the uterine spiral arteries, determines a series of systemic repercussions that compound the various forms of preeclampsia presentation. In recent years, the use of acetylsalicylic acid to prevent cases of early onset of the disease has been consolidated and, alongside, studies have advanced the development of accessible and effective methods of identifying women at risk of preeclampsia. The aim of this review is to discuss updates on the occurrence, concept, pathophysiology, repercussion, prevention, and prediction of preeclampsia.http://dx.doi.org/10.1155/2018/6268276
spellingShingle J. Mayrink
M. L. Costa
J. G. Cecatti
Preeclampsia in 2018: Revisiting Concepts, Physiopathology, and Prediction
The Scientific World Journal
title Preeclampsia in 2018: Revisiting Concepts, Physiopathology, and Prediction
title_full Preeclampsia in 2018: Revisiting Concepts, Physiopathology, and Prediction
title_fullStr Preeclampsia in 2018: Revisiting Concepts, Physiopathology, and Prediction
title_full_unstemmed Preeclampsia in 2018: Revisiting Concepts, Physiopathology, and Prediction
title_short Preeclampsia in 2018: Revisiting Concepts, Physiopathology, and Prediction
title_sort preeclampsia in 2018 revisiting concepts physiopathology and prediction
url http://dx.doi.org/10.1155/2018/6268276
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