A constitutive heterochromatic region shapes genome organization and impacts gene expression in Neurospora crassa

A constitutive heterochromatic region shapes genome organization and impacts gene expression in Neurospora crassa

Abstract Background Organization of the eukaryotic genome is essential for proper function, including gene expression. In metazoans, chromatin loops and Topologically Associated Domains (TADs) organize genes into transcription factories, while chromosomes occupy nuclear territories in which silent h...

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Bibliographic Details
Main Authors: Andrew T. Reckard, Abhishek Pandeya, Jacob M. Voris, Carlos G. Gonzalez Cruz, Oluwatosin Oluwadare, Andrew D. Klocko
Format: Article
Language:English
Published: BMC 2024-12-01
Series:BMC Genomics
Subjects:
Genome organization
Chromosome conformation
Heterochromatin
Neurospora crassa
Gene expression
Online Access:https://doi.org/10.1186/s12864-024-11110-7
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