Migraine-Asthma Comorbidity and Risk of Hypertensive Disorders of Pregnancy
Background. To evaluate the association of migraine and asthma and to estimate the risk of hypertensive disorders of pregnancy in relation to maternal comorbid migraine and asthma. Methods. Reproductive age women (N=3.731) were interviewed during early pregnancy. At the time of interview, we ascerta...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Journal of Pregnancy |
| Online Access: | http://dx.doi.org/10.1155/2012/858097 |
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| _version_ | 1832552669719298048 |
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| author | Stefanie Czerwinski Jolana Gollero Chunfang Qiu Tanya K. Sorensen Michelle A. Williams |
| author_facet | Stefanie Czerwinski Jolana Gollero Chunfang Qiu Tanya K. Sorensen Michelle A. Williams |
| author_sort | Stefanie Czerwinski |
| collection | DOAJ |
| description | Background. To evaluate the association of migraine and asthma and to estimate the risk of hypertensive disorders of pregnancy in relation to maternal comorbid migraine and asthma. Methods. Reproductive age women (N=3.731) were interviewed during early pregnancy. At the time of interview, we ascertained participants’ migraine and asthma status. From medical records, we collected information to allow the diagnosis of pregnancy-induced hypertension (PIH) and preeclampsia. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using logistic regression procedures. Results. After adjusting for confounders, migraineurs had 1.38-fold increased odds of asthma as compared with nonmigraineurs (95% CI 1.09–1.38). The odds of hypertensive disorders of pregnancy were highest among women with comorbid migraine-asthma. The ORs for PIH preeclampsia and the two disorders combined were 2.53 (95% CI 1.39–4.61), 3.53 (95% CI 1.51–8.24), and 2.64 (95% CI 1.56–4.47), respectively, for women with comorbid migraine-asthma as compared with those who had neither disorder. Conclusion. These findings confirm prior reports and extend the literature by documenting particularly high odds of pregnancy-induced hypertension and preeclampsia among women with comorbid migraine-asthma. Increased knowledge about the prevalence and sequelae of comorbidities during pregnancy may lead to improved symptom management and perinatal outcomes. |
| format | Article |
| id | doaj-art-ca093ddfef8f46ab975569963f07dede |
| institution | Kabale University |
| issn | 2090-2727 2090-2735 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Pregnancy |
| spelling | doaj-art-ca093ddfef8f46ab975569963f07dede2025-02-03T05:58:15ZengWileyJournal of Pregnancy2090-27272090-27352012-01-01201210.1155/2012/858097858097Migraine-Asthma Comorbidity and Risk of Hypertensive Disorders of PregnancyStefanie Czerwinski0Jolana Gollero1Chunfang Qiu2Tanya K. Sorensen3Michelle A. Williams4Multidisciplinary International Research Training Program, University of Washington, Seattle, WA 98195, USAMultidisciplinary International Research Training Program, University of Washington, Seattle, WA 98195, USACenter for Perinatal Studies, Swedish Medical Center, Seattle, WA 98104, USACenter for Perinatal Studies, Swedish Medical Center, Seattle, WA 98104, USAMultidisciplinary International Research Training Program, University of Washington, Seattle, WA 98195, USABackground. To evaluate the association of migraine and asthma and to estimate the risk of hypertensive disorders of pregnancy in relation to maternal comorbid migraine and asthma. Methods. Reproductive age women (N=3.731) were interviewed during early pregnancy. At the time of interview, we ascertained participants’ migraine and asthma status. From medical records, we collected information to allow the diagnosis of pregnancy-induced hypertension (PIH) and preeclampsia. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using logistic regression procedures. Results. After adjusting for confounders, migraineurs had 1.38-fold increased odds of asthma as compared with nonmigraineurs (95% CI 1.09–1.38). The odds of hypertensive disorders of pregnancy were highest among women with comorbid migraine-asthma. The ORs for PIH preeclampsia and the two disorders combined were 2.53 (95% CI 1.39–4.61), 3.53 (95% CI 1.51–8.24), and 2.64 (95% CI 1.56–4.47), respectively, for women with comorbid migraine-asthma as compared with those who had neither disorder. Conclusion. These findings confirm prior reports and extend the literature by documenting particularly high odds of pregnancy-induced hypertension and preeclampsia among women with comorbid migraine-asthma. Increased knowledge about the prevalence and sequelae of comorbidities during pregnancy may lead to improved symptom management and perinatal outcomes.http://dx.doi.org/10.1155/2012/858097 |
| spellingShingle | Stefanie Czerwinski Jolana Gollero Chunfang Qiu Tanya K. Sorensen Michelle A. Williams Migraine-Asthma Comorbidity and Risk of Hypertensive Disorders of Pregnancy Journal of Pregnancy |
| title | Migraine-Asthma Comorbidity and Risk of Hypertensive Disorders of Pregnancy |
| title_full | Migraine-Asthma Comorbidity and Risk of Hypertensive Disorders of Pregnancy |
| title_fullStr | Migraine-Asthma Comorbidity and Risk of Hypertensive Disorders of Pregnancy |
| title_full_unstemmed | Migraine-Asthma Comorbidity and Risk of Hypertensive Disorders of Pregnancy |
| title_short | Migraine-Asthma Comorbidity and Risk of Hypertensive Disorders of Pregnancy |
| title_sort | migraine asthma comorbidity and risk of hypertensive disorders of pregnancy |
| url | http://dx.doi.org/10.1155/2012/858097 |
| work_keys_str_mv | AT stefanieczerwinski migraineasthmacomorbidityandriskofhypertensivedisordersofpregnancy AT jolanagollero migraineasthmacomorbidityandriskofhypertensivedisordersofpregnancy AT chunfangqiu migraineasthmacomorbidityandriskofhypertensivedisordersofpregnancy AT tanyaksorensen migraineasthmacomorbidityandriskofhypertensivedisordersofpregnancy AT michelleawilliams migraineasthmacomorbidityandriskofhypertensivedisordersofpregnancy |