A Sustainable Approach to Glucose Biosensors: Utilizing Coconut Shell Activated Carbon and NiCaFe₂O₄ Nanoparticles

Diabetes-related mortality can be significantly reduced through early detection of blood glucose levels. This study presents a sustainable approach to glucose biosensors by utilizing coconut shell activated carbon as the working electrode material in a carbon paste electrode for electrochemical gluc...

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Main Authors: Fatoni Amin, Hutama David, Hermawan Dadan, Samanman Saluma, Dwi Anggraeni Mekar
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:E3S Web of Conferences
Online Access:https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/09/e3sconf_icma-sure2024_02002.pdf
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author Fatoni Amin
Hutama David
Hermawan Dadan
Samanman Saluma
Dwi Anggraeni Mekar
author_facet Fatoni Amin
Hutama David
Hermawan Dadan
Samanman Saluma
Dwi Anggraeni Mekar
author_sort Fatoni Amin
collection DOAJ
description Diabetes-related mortality can be significantly reduced through early detection of blood glucose levels. This study presents a sustainable approach to glucose biosensors by utilizing coconut shell activated carbon as the working electrode material in a carbon paste electrode for electrochemical glucose detection via cyclic voltammetry. The performance of the electrode was further enhanced with NiCaFe₂ O₄ nanoparticles to improve electron transfer and redox potential. The optimized electrode consisted of a 2:1 ratio of activated carbon to paraffin, incorporating 16% NiCaFe₂ O₄ nanoparticles. Detection of hydrogen peroxide using this modified electrode exhibited an oxidation peak at 0.16 V and a reduction peak at -0.35 V. Optimal glucose detection conditions were achieved in 100 mM phosphate buffer at pH 7.5. Glucose oxidase was immobilized on the modified electrode, showing a linear response for glucose detection at the oxidation peak of 0.66 V. This sustainable biosensor demonstrated high sensitivity and potential for low- cost, eco-friendly glucose monitoring applications.
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institution Kabale University
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publishDate 2025-01-01
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series E3S Web of Conferences
spelling doaj-art-ca037d8a52a946bcbcfb2e2392e2a2b92025-02-05T10:49:56ZengEDP SciencesE3S Web of Conferences2267-12422025-01-016090200210.1051/e3sconf/202560902002e3sconf_icma-sure2024_02002A Sustainable Approach to Glucose Biosensors: Utilizing Coconut Shell Activated Carbon and NiCaFe₂O₄ NanoparticlesFatoni Amin0Hutama David1Hermawan Dadan2Samanman Saluma3Dwi Anggraeni Mekar4Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Jenderal SoedirmanDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Jenderal SoedirmanDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Jenderal SoedirmanFaculty of Science and Technology, Princess of Naradhiwas UniversityDepartment of Nursing, Faculty of Health Sciences, Universitas Jenderal SoedirmanDiabetes-related mortality can be significantly reduced through early detection of blood glucose levels. This study presents a sustainable approach to glucose biosensors by utilizing coconut shell activated carbon as the working electrode material in a carbon paste electrode for electrochemical glucose detection via cyclic voltammetry. The performance of the electrode was further enhanced with NiCaFe₂ O₄ nanoparticles to improve electron transfer and redox potential. The optimized electrode consisted of a 2:1 ratio of activated carbon to paraffin, incorporating 16% NiCaFe₂ O₄ nanoparticles. Detection of hydrogen peroxide using this modified electrode exhibited an oxidation peak at 0.16 V and a reduction peak at -0.35 V. Optimal glucose detection conditions were achieved in 100 mM phosphate buffer at pH 7.5. Glucose oxidase was immobilized on the modified electrode, showing a linear response for glucose detection at the oxidation peak of 0.66 V. This sustainable biosensor demonstrated high sensitivity and potential for low- cost, eco-friendly glucose monitoring applications.https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/09/e3sconf_icma-sure2024_02002.pdf
spellingShingle Fatoni Amin
Hutama David
Hermawan Dadan
Samanman Saluma
Dwi Anggraeni Mekar
A Sustainable Approach to Glucose Biosensors: Utilizing Coconut Shell Activated Carbon and NiCaFe₂O₄ Nanoparticles
E3S Web of Conferences
title A Sustainable Approach to Glucose Biosensors: Utilizing Coconut Shell Activated Carbon and NiCaFe₂O₄ Nanoparticles
title_full A Sustainable Approach to Glucose Biosensors: Utilizing Coconut Shell Activated Carbon and NiCaFe₂O₄ Nanoparticles
title_fullStr A Sustainable Approach to Glucose Biosensors: Utilizing Coconut Shell Activated Carbon and NiCaFe₂O₄ Nanoparticles
title_full_unstemmed A Sustainable Approach to Glucose Biosensors: Utilizing Coconut Shell Activated Carbon and NiCaFe₂O₄ Nanoparticles
title_short A Sustainable Approach to Glucose Biosensors: Utilizing Coconut Shell Activated Carbon and NiCaFe₂O₄ Nanoparticles
title_sort sustainable approach to glucose biosensors utilizing coconut shell activated carbon and nicafe₂o₄ nanoparticles
url https://www.e3s-conferences.org/articles/e3sconf/pdf/2025/09/e3sconf_icma-sure2024_02002.pdf
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