The level of the autoantibodies to antigenes of the thyroid gland at metabolic syndrome with deficiency of estrogens and the hypothyroidism
It has been shown that the concentration of autoantibodies to thyroperoxidase was significantly increased in rats with estrogen-deficiency. The combination of hypoestrogenia and metabolic syndrome with hypothyroidism intensified destructive processes in the thyroid gland. 17β-estradiol had the prote...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
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Zaporizhzhia State Medical and Pharmaceutical University
2012-08-01
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| Series: | Patologìâ |
| Subjects: | |
| Online Access: | http://pat.zsmu.edu.ua/article/view/16759/14280 |
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| Summary: | It has been shown that the concentration of autoantibodies to thyroperoxidase was significantly increased in rats with estrogen-deficiency. The combination of hypoestrogenia and metabolic syndrome with hypothyroidism intensified destructive processes in the thyroid gland. 17β-estradiol had the protective effect to the damaged thyroid gland in ovarioectomized animals with metabolic syndrome and hypothyroidism that was confirmed by significant reduction of concentration of autoantibodies to thyroperoxidase. |
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| ISSN: | 2306-8027 2310-1237 |