SLEPR: a sample-level enrichment-based pathway ranking method -- seeking biological themes through pathway-level consistency.

Analysis of microarray and other high throughput data often involves identification of genes consistently up or down-regulated across samples as the first step in extraction of biological meaning. This gene-level paradigm can be limited as a result of valid sample fluctuations and biological complex...

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Bibliographic Details
Main Authors: Ming Yi, Robert M Stephens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-09-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003288&type=printable
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