Self-Reported Executive Functioning in Everyday Life in Parkinson’s Disease after Three Months of Subthalamic Deep Brain Stimulation
Objective. Studies on the effect of subthalamic deep brain stimulation (STN-DBS) on executive functioning in Parkinson’s disease (PD) are still controversial. In this study we compared self-reported daily executive functioning in PD patients before and after three months of STN-DBS. We also examine...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.1155/2015/461453 |
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| author | Uyen Ha Gia Pham Stein Andersson Mathias Toft Are Hugo Pripp Ane Eidahl Konglund Espen Dietrichs Ulrik Fredrik Malt Inger Marie Skogseid Ira Ronit Hebolt Haraldsen Anne-Kristin Solbakk |
| author_facet | Uyen Ha Gia Pham Stein Andersson Mathias Toft Are Hugo Pripp Ane Eidahl Konglund Espen Dietrichs Ulrik Fredrik Malt Inger Marie Skogseid Ira Ronit Hebolt Haraldsen Anne-Kristin Solbakk |
| author_sort | Uyen Ha Gia Pham |
| collection | DOAJ |
| description | Objective. Studies on the effect of subthalamic deep brain stimulation (STN-DBS) on executive functioning in Parkinson’s disease (PD) are still controversial. In this study we compared self-reported daily executive functioning in PD patients before and after three months of STN-DBS. We also examined whether executive functioning in everyday life was associated with motor symptoms, apathy, and psychiatric symptoms. Method. 40 PD patients were examined with the Behavior Rating Inventory of Executive Function-Adult Version (BRIEF-A), the Symptom Checklist 90-Revised (SCL-90-R), and the Apathy Evaluation Scale (AES-S). Results. PD patients reported significant improvement in daily life executive functioning after 3 months of STN-DBS. Anxiety scores significantly declined, while other psychiatric symptoms remained unchanged. The improvement of self-reported executive functioning did not correlate with motor improvement after STN-DBS. Apathy scores remained unchanged after surgery. Only preoperative depressed mood had predictive value to the improvement of executive function and appears to prevent potentially favorable outcomes from STN-DBS on some aspects of executive function. Conclusion. PD patients being screened for STN-DBS surgery should be evaluated with regard to self-reported executive functioning. Depressive symptoms in presurgical PD patients should be treated. Complementary information about daily life executive functioning in PD patients might enhance further treatment planning of STN-DBS. |
| format | Article |
| id | doaj-art-c9d638cc88154e5c9a59e1292ede17db |
| institution | Kabale University |
| issn | 2090-8083 2042-0080 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-c9d638cc88154e5c9a59e1292ede17db2025-02-03T01:30:08ZengWileyParkinson's Disease2090-80832042-00802015-01-01201510.1155/2015/461453461453Self-Reported Executive Functioning in Everyday Life in Parkinson’s Disease after Three Months of Subthalamic Deep Brain StimulationUyen Ha Gia Pham0Stein Andersson1Mathias Toft2Are Hugo Pripp3Ane Eidahl Konglund4Espen Dietrichs5Ulrik Fredrik Malt6Inger Marie Skogseid7Ira Ronit Hebolt Haraldsen8Anne-Kristin Solbakk9Department of Psychosomatic Medicine, Oslo University Hospital-Rikshospitalet, 0424 Oslo, NorwayDepartment of Psychosomatic Medicine, Oslo University Hospital-Rikshospitalet, 0424 Oslo, NorwayDepartment of Neurology, Oslo University Hospital-Rikshospitalet, 0424 Oslo, NorwayOslo Centre of Biostatistics and Epidemiology, Oslo University Hospital, 0424 Oslo, NorwayDepartment of Neurosurgery, Oslo University Hospital-Rikshospitalet, 0424 Oslo, NorwayInstitute of Clinical Medicine, University of Oslo, 0316 Oslo, NorwayDepartment of Psychosomatic Medicine, Oslo University Hospital-Rikshospitalet, 0424 Oslo, NorwayDepartment of Neurology, Oslo University Hospital-Rikshospitalet, 0424 Oslo, NorwayDepartment of Psychosomatic Medicine, Oslo University Hospital-Rikshospitalet, 0424 Oslo, NorwayDepartment of Psychosomatic Medicine, Oslo University Hospital-Rikshospitalet, 0424 Oslo, NorwayObjective. Studies on the effect of subthalamic deep brain stimulation (STN-DBS) on executive functioning in Parkinson’s disease (PD) are still controversial. In this study we compared self-reported daily executive functioning in PD patients before and after three months of STN-DBS. We also examined whether executive functioning in everyday life was associated with motor symptoms, apathy, and psychiatric symptoms. Method. 40 PD patients were examined with the Behavior Rating Inventory of Executive Function-Adult Version (BRIEF-A), the Symptom Checklist 90-Revised (SCL-90-R), and the Apathy Evaluation Scale (AES-S). Results. PD patients reported significant improvement in daily life executive functioning after 3 months of STN-DBS. Anxiety scores significantly declined, while other psychiatric symptoms remained unchanged. The improvement of self-reported executive functioning did not correlate with motor improvement after STN-DBS. Apathy scores remained unchanged after surgery. Only preoperative depressed mood had predictive value to the improvement of executive function and appears to prevent potentially favorable outcomes from STN-DBS on some aspects of executive function. Conclusion. PD patients being screened for STN-DBS surgery should be evaluated with regard to self-reported executive functioning. Depressive symptoms in presurgical PD patients should be treated. Complementary information about daily life executive functioning in PD patients might enhance further treatment planning of STN-DBS.http://dx.doi.org/10.1155/2015/461453 |
| spellingShingle | Uyen Ha Gia Pham Stein Andersson Mathias Toft Are Hugo Pripp Ane Eidahl Konglund Espen Dietrichs Ulrik Fredrik Malt Inger Marie Skogseid Ira Ronit Hebolt Haraldsen Anne-Kristin Solbakk Self-Reported Executive Functioning in Everyday Life in Parkinson’s Disease after Three Months of Subthalamic Deep Brain Stimulation Parkinson's Disease |
| title | Self-Reported Executive Functioning in Everyday Life in Parkinson’s Disease after Three Months of Subthalamic Deep Brain Stimulation |
| title_full | Self-Reported Executive Functioning in Everyday Life in Parkinson’s Disease after Three Months of Subthalamic Deep Brain Stimulation |
| title_fullStr | Self-Reported Executive Functioning in Everyday Life in Parkinson’s Disease after Three Months of Subthalamic Deep Brain Stimulation |
| title_full_unstemmed | Self-Reported Executive Functioning in Everyday Life in Parkinson’s Disease after Three Months of Subthalamic Deep Brain Stimulation |
| title_short | Self-Reported Executive Functioning in Everyday Life in Parkinson’s Disease after Three Months of Subthalamic Deep Brain Stimulation |
| title_sort | self reported executive functioning in everyday life in parkinson s disease after three months of subthalamic deep brain stimulation |
| url | http://dx.doi.org/10.1155/2015/461453 |
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