Extreme Procalcitonin Elevation without Proven Bacterial Infection Related to Amphetamine Abuse
Systemic inflammatory response with rhabdomyolysis and consequent multiorgan failure is a known sequela of psychotropic drug abuse. However, in cases with uncertain past medical history the initial diagnosis can be challenging. Here we report the case of a 21-year-old male who was admitted to the in...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Critical Care |
| Online Access: | http://dx.doi.org/10.1155/2014/179313 |
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| _version_ | 1832564635705802752 |
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| author | András Lovas Zsuzsanna Ágoston Klára Késmárky Péter Hankovszky Zsolt Molnár |
| author_facet | András Lovas Zsuzsanna Ágoston Klára Késmárky Péter Hankovszky Zsolt Molnár |
| author_sort | András Lovas |
| collection | DOAJ |
| description | Systemic inflammatory response with rhabdomyolysis and consequent multiorgan failure is a known sequela of psychotropic drug abuse. However, in cases with uncertain past medical history the initial diagnosis can be challenging. Here we report the case of a 21-year-old male who was admitted to the intensive care unit with severe neurological impairment caused by amphetamine intoxication. First laboratory investigations revealed extremely high serum procalcitonin (PCT) levels reaching a maximum concentration of 1640 ng/mL on the second day of observation. Although PCT has high sensitivity and specificity in differentiating bacterial sepsis from nonbacterial inflammation, our case report shows for the first time that it can be extremely elevated following serious amphetamine intoxication without bacterial infection. |
| format | Article |
| id | doaj-art-c9d38f2565774c0bb0c8d6e2a97c28df |
| institution | Kabale University |
| issn | 2090-6420 2090-6439 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Critical Care |
| spelling | doaj-art-c9d38f2565774c0bb0c8d6e2a97c28df2025-02-03T01:10:32ZengWileyCase Reports in Critical Care2090-64202090-64392014-01-01201410.1155/2014/179313179313Extreme Procalcitonin Elevation without Proven Bacterial Infection Related to Amphetamine AbuseAndrás Lovas0Zsuzsanna Ágoston1Klára Késmárky2Péter Hankovszky3Zsolt Molnár4Department of Anaesthesiology and Intensive Therapy, University of Szeged, Semmelweis Utca 6, Szeged 6722, HungaryDepartment of Anaesthesiology and Intensive Therapy, University of Szeged, Semmelweis Utca 6, Szeged 6722, HungaryDepartment of Anaesthesiology and Intensive Therapy, University of Szeged, Semmelweis Utca 6, Szeged 6722, HungaryDepartment of Anaesthesiology and Intensive Therapy, University of Szeged, Semmelweis Utca 6, Szeged 6722, HungaryDepartment of Anaesthesiology and Intensive Therapy, University of Szeged, Semmelweis Utca 6, Szeged 6722, HungarySystemic inflammatory response with rhabdomyolysis and consequent multiorgan failure is a known sequela of psychotropic drug abuse. However, in cases with uncertain past medical history the initial diagnosis can be challenging. Here we report the case of a 21-year-old male who was admitted to the intensive care unit with severe neurological impairment caused by amphetamine intoxication. First laboratory investigations revealed extremely high serum procalcitonin (PCT) levels reaching a maximum concentration of 1640 ng/mL on the second day of observation. Although PCT has high sensitivity and specificity in differentiating bacterial sepsis from nonbacterial inflammation, our case report shows for the first time that it can be extremely elevated following serious amphetamine intoxication without bacterial infection.http://dx.doi.org/10.1155/2014/179313 |
| spellingShingle | András Lovas Zsuzsanna Ágoston Klára Késmárky Péter Hankovszky Zsolt Molnár Extreme Procalcitonin Elevation without Proven Bacterial Infection Related to Amphetamine Abuse Case Reports in Critical Care |
| title | Extreme Procalcitonin Elevation without Proven Bacterial Infection Related to Amphetamine Abuse |
| title_full | Extreme Procalcitonin Elevation without Proven Bacterial Infection Related to Amphetamine Abuse |
| title_fullStr | Extreme Procalcitonin Elevation without Proven Bacterial Infection Related to Amphetamine Abuse |
| title_full_unstemmed | Extreme Procalcitonin Elevation without Proven Bacterial Infection Related to Amphetamine Abuse |
| title_short | Extreme Procalcitonin Elevation without Proven Bacterial Infection Related to Amphetamine Abuse |
| title_sort | extreme procalcitonin elevation without proven bacterial infection related to amphetamine abuse |
| url | http://dx.doi.org/10.1155/2014/179313 |
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