Generation of Inheritable A-to-G Transitions Using Adenine Base Editing and NG-PAM Cas9 in Arabidopsis thaliana
Towards precise genome editing, base editors have been developed by fusing catalytically compromised Cas9 with deaminase components, mediating C-to-T (cytosine base editors) or A-to-G (adenine base editors) transition. We developed a set of vectors consisting of a 5′-NG-3′ PAM-recognizing variant of...
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| Main Authors: | Yi Yun Tan, Yin Yin Liew, Rachelle R. Q. Lee, Baptiste Castel, Nga Man Chan, Wei-Lin Wan, Yizhong Zhang, Donghui Hu, Persis Chan, Sang-Tae Kim, Eunyoung Chae |
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| Format: | Article |
| Language: | English |
| Published: |
The American Phytopathological Society
2025-01-01
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| Series: | Molecular Plant-Microbe Interactions |
| Subjects: | |
| Online Access: | https://apsjournals.apsnet.org/doi/10.1094/MPMI-10-24-0127-TA |
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