0.5 V Digitally-Tunable Filters for Biomedical Applications Exploiting Segmented Duty-Cycled Resistors

In this paper, we present the design and the experimental validation of a biquad filter for biomedical applications that takes advantage of segmented duty-cycled resistors to allow for digital tuning over a wide range of the cutoff frequency (<inline-formula> <tex-math notation="LaTeX&...

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Main Authors: Alessandro Fava, Francesco Centurelli, Giuseppe Scotti
Format: Article
Language:English
Published: IEEE 2025-01-01
Series:IEEE Access
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Online Access:https://ieeexplore.ieee.org/document/10849568/
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author Alessandro Fava
Francesco Centurelli
Giuseppe Scotti
author_facet Alessandro Fava
Francesco Centurelli
Giuseppe Scotti
author_sort Alessandro Fava
collection DOAJ
description In this paper, we present the design and the experimental validation of a biquad filter for biomedical applications that takes advantage of segmented duty-cycled resistors to allow for digital tuning over a wide range of the cutoff frequency (<inline-formula> <tex-math notation="LaTeX">$f_{0}$ </tex-math></inline-formula>), quality factor (Q), and gain (K). Additionally, we report on the experimental findings for an 8th-order band pass filter that was created to extract the epilepsy biomarker, related to the fast ripple band (250 Hz&#x2013;500 Hz). The results of measurements on a prototype chip, implemented in a commercial 130 nm CMOS technology with a supply voltage of 0.5 V and a power consumption of 120 nW, confirm that the <inline-formula> <tex-math notation="LaTeX">$f_{0}$ </tex-math></inline-formula> of the proposed biquad filter can be digitally tuned from 15 Hz up to 517 Hz, whereas the Q can be tuned from 0.7 up to 13. A comparison against the state of the art has shown that the proposed biquad filter exhibits the lowest area, with the highest Q, and can be tuned at the lowest <inline-formula> <tex-math notation="LaTeX">$f_{0}$ </tex-math></inline-formula>. It also exhibits the unique feature to allow for independent tunability of <inline-formula> <tex-math notation="LaTeX">$f_{0}$ </tex-math></inline-formula>, Q, and K by varying the duty-cycle of digital control signals. The 8th-order filter, implemented with 4 cascaded instances of the proposed biquad filter, guarantees an attenuation higher than 30 dB at <inline-formula> <tex-math notation="LaTeX">$f_{0}$ </tex-math></inline-formula>/2 and 2f0 with a power consumption of 480 nW, and an area footprint of 0.152 mm2, thus satisfying the requirements to extract the epilepsy biomarker in closed-loop deep brain stimulation systems.
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spelling doaj-art-c9af51f172bf43859d142e435d6875732025-01-31T00:02:04ZengIEEEIEEE Access2169-35362025-01-0113179961800410.1109/ACCESS.2025.3532824108495680.5 V Digitally-Tunable Filters for Biomedical Applications Exploiting Segmented Duty-Cycled ResistorsAlessandro Fava0https://orcid.org/0000-0002-5454-9643Francesco Centurelli1https://orcid.org/0000-0003-3880-2546Giuseppe Scotti2https://orcid.org/0000-0002-5650-8212Department of Information, Electronics and Telecommunication Engineering, Sapienza University of Rome, Rome, ItalyDepartment of Information, Electronics and Telecommunication Engineering, Sapienza University of Rome, Rome, ItalyDepartment of Information, Electronics and Telecommunication Engineering, Sapienza University of Rome, Rome, ItalyIn this paper, we present the design and the experimental validation of a biquad filter for biomedical applications that takes advantage of segmented duty-cycled resistors to allow for digital tuning over a wide range of the cutoff frequency (<inline-formula> <tex-math notation="LaTeX">$f_{0}$ </tex-math></inline-formula>), quality factor (Q), and gain (K). Additionally, we report on the experimental findings for an 8th-order band pass filter that was created to extract the epilepsy biomarker, related to the fast ripple band (250 Hz&#x2013;500 Hz). The results of measurements on a prototype chip, implemented in a commercial 130 nm CMOS technology with a supply voltage of 0.5 V and a power consumption of 120 nW, confirm that the <inline-formula> <tex-math notation="LaTeX">$f_{0}$ </tex-math></inline-formula> of the proposed biquad filter can be digitally tuned from 15 Hz up to 517 Hz, whereas the Q can be tuned from 0.7 up to 13. A comparison against the state of the art has shown that the proposed biquad filter exhibits the lowest area, with the highest Q, and can be tuned at the lowest <inline-formula> <tex-math notation="LaTeX">$f_{0}$ </tex-math></inline-formula>. It also exhibits the unique feature to allow for independent tunability of <inline-formula> <tex-math notation="LaTeX">$f_{0}$ </tex-math></inline-formula>, Q, and K by varying the duty-cycle of digital control signals. The 8th-order filter, implemented with 4 cascaded instances of the proposed biquad filter, guarantees an attenuation higher than 30 dB at <inline-formula> <tex-math notation="LaTeX">$f_{0}$ </tex-math></inline-formula>/2 and 2f0 with a power consumption of 480 nW, and an area footprint of 0.152 mm2, thus satisfying the requirements to extract the epilepsy biomarker in closed-loop deep brain stimulation systems.https://ieeexplore.ieee.org/document/10849568/Low-voltageactive filtersbiomedical applicationslarge time constantsintegrated circuitsswitched-resistor
spellingShingle Alessandro Fava
Francesco Centurelli
Giuseppe Scotti
0.5 V Digitally-Tunable Filters for Biomedical Applications Exploiting Segmented Duty-Cycled Resistors
IEEE Access
Low-voltage
active filters
biomedical applications
large time constants
integrated circuits
switched-resistor
title 0.5 V Digitally-Tunable Filters for Biomedical Applications Exploiting Segmented Duty-Cycled Resistors
title_full 0.5 V Digitally-Tunable Filters for Biomedical Applications Exploiting Segmented Duty-Cycled Resistors
title_fullStr 0.5 V Digitally-Tunable Filters for Biomedical Applications Exploiting Segmented Duty-Cycled Resistors
title_full_unstemmed 0.5 V Digitally-Tunable Filters for Biomedical Applications Exploiting Segmented Duty-Cycled Resistors
title_short 0.5 V Digitally-Tunable Filters for Biomedical Applications Exploiting Segmented Duty-Cycled Resistors
title_sort 0 5 v digitally tunable filters for biomedical applications exploiting segmented duty cycled resistors
topic Low-voltage
active filters
biomedical applications
large time constants
integrated circuits
switched-resistor
url https://ieeexplore.ieee.org/document/10849568/
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AT giuseppescotti 05vdigitallytunablefiltersforbiomedicalapplicationsexploitingsegmenteddutycycledresistors