Hypoxia and TNF‐alpha modulate extracellular vesicle release from human induced pluripotent stem cell‐derived cardiomyocytes

Hypoxia and TNF‐alpha modulate extracellular vesicle release from human induced pluripotent stem cell‐derived cardiomyocytes

Abstract Extracellular vesicles (EVs) have emerged as important mediators of intercellular communication in the heart under homeostatic and pathological conditions, such as myocardial infarction (MI). However, the basic mechanisms driving cardiomyocyte‐derived EV (CM‐EV) production following stress...

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Bibliographic Details
Main Authors: Margarida Viola, Maarten P. Bebelman, Renee G. C. Maas, Willemijn S. deVoogt, Frederik J. Verweij, Cor S. Seinen, Saskia C. A. deJager, Pieter Vader, Dirk Michiel Pegtel, Joost Petrus Gerardus Sluijter
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Journal of Extracellular Vesicles
Subjects:
cardiomyocytes
EV biogenesis
extracellular vesicles
myocardial infarction
NanoLuc
Online Access:https://doi.org/10.1002/jev2.70000
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