Interventional Protocol for Treatment of Complications after Esophagojejunostomy for Esophagogastric Carcinoma

Background. Anastomotic stenosis and leakage are rare complications after esophagojejunostomy. The management of complications after esophagojejunostomy remains a challenge. We evaluated the outcomes and clinical effectiveness of an alternative interventional protocol. Objectives. To determine the s...

Full description

Saved in:
Bibliographic Details
Main Authors: Yonghua Bi, Jindong Li, Mengfei Yi, Zepeng Yu, Xinwei Han, Jianzhuang Ren
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2019/1465301
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832562637163986944
author Yonghua Bi
Jindong Li
Mengfei Yi
Zepeng Yu
Xinwei Han
Jianzhuang Ren
author_facet Yonghua Bi
Jindong Li
Mengfei Yi
Zepeng Yu
Xinwei Han
Jianzhuang Ren
author_sort Yonghua Bi
collection DOAJ
description Background. Anastomotic stenosis and leakage are rare complications after esophagojejunostomy. The management of complications after esophagojejunostomy remains a challenge. We evaluated the outcomes and clinical effectiveness of an alternative interventional protocol. Objectives. To determine the safety and efficacy of interventional treatment for the management of complications after esophagojejunostomy. Methods. This study included 24 consecutive patients with complications after esophagojejunostomy treated using interventional protocol. Patients received balloon dilation or stenting for anastomotic stenosis. Patients with anastomotic leakage received three-tube placement or retrievable covered esophageal stent placement, followed by abscess drainage, nutritional support, and anti-inflammatory treatment. The three tubes and esophageal stents were removed after leakage healing and stenosis ceased. Results. Thirteen patients received three-tube method, and 16 patients received covered stent placement. All procedures were technically successful, except for a failure of Y-type esophageal stent placement in one patient. The median retention time of stent and abscess drainage tube was 67.5 days and 87 days, respectively. No perioperative death, esophageal rupture, or massive hemorrhage was found during procedures. During follow-up, 14 patients died of cancer recurrence, and one died of severe pulmonary infection. The 1-, 3-, 5-year survival rates were 39.5%, 23.7%, and 23.7%, respectively. Conclusion. Interventional protocol is safe, feasible, and efficacious for treatment of complications after esophagojejunostomy.
format Article
id doaj-art-c9988f48c95d4400bb7457ec89897065
institution Kabale University
issn 1687-6121
1687-630X
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Gastroenterology Research and Practice
spelling doaj-art-c9988f48c95d4400bb7457ec898970652025-02-03T01:22:14ZengWileyGastroenterology Research and Practice1687-61211687-630X2019-01-01201910.1155/2019/14653011465301Interventional Protocol for Treatment of Complications after Esophagojejunostomy for Esophagogastric CarcinomaYonghua Bi0Jindong Li1Mengfei Yi2Zepeng Yu3Xinwei Han4Jianzhuang Ren5Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Thoracic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaBackground. Anastomotic stenosis and leakage are rare complications after esophagojejunostomy. The management of complications after esophagojejunostomy remains a challenge. We evaluated the outcomes and clinical effectiveness of an alternative interventional protocol. Objectives. To determine the safety and efficacy of interventional treatment for the management of complications after esophagojejunostomy. Methods. This study included 24 consecutive patients with complications after esophagojejunostomy treated using interventional protocol. Patients received balloon dilation or stenting for anastomotic stenosis. Patients with anastomotic leakage received three-tube placement or retrievable covered esophageal stent placement, followed by abscess drainage, nutritional support, and anti-inflammatory treatment. The three tubes and esophageal stents were removed after leakage healing and stenosis ceased. Results. Thirteen patients received three-tube method, and 16 patients received covered stent placement. All procedures were technically successful, except for a failure of Y-type esophageal stent placement in one patient. The median retention time of stent and abscess drainage tube was 67.5 days and 87 days, respectively. No perioperative death, esophageal rupture, or massive hemorrhage was found during procedures. During follow-up, 14 patients died of cancer recurrence, and one died of severe pulmonary infection. The 1-, 3-, 5-year survival rates were 39.5%, 23.7%, and 23.7%, respectively. Conclusion. Interventional protocol is safe, feasible, and efficacious for treatment of complications after esophagojejunostomy.http://dx.doi.org/10.1155/2019/1465301
spellingShingle Yonghua Bi
Jindong Li
Mengfei Yi
Zepeng Yu
Xinwei Han
Jianzhuang Ren
Interventional Protocol for Treatment of Complications after Esophagojejunostomy for Esophagogastric Carcinoma
Gastroenterology Research and Practice
title Interventional Protocol for Treatment of Complications after Esophagojejunostomy for Esophagogastric Carcinoma
title_full Interventional Protocol for Treatment of Complications after Esophagojejunostomy for Esophagogastric Carcinoma
title_fullStr Interventional Protocol for Treatment of Complications after Esophagojejunostomy for Esophagogastric Carcinoma
title_full_unstemmed Interventional Protocol for Treatment of Complications after Esophagojejunostomy for Esophagogastric Carcinoma
title_short Interventional Protocol for Treatment of Complications after Esophagojejunostomy for Esophagogastric Carcinoma
title_sort interventional protocol for treatment of complications after esophagojejunostomy for esophagogastric carcinoma
url http://dx.doi.org/10.1155/2019/1465301
work_keys_str_mv AT yonghuabi interventionalprotocolfortreatmentofcomplicationsafteresophagojejunostomyforesophagogastriccarcinoma
AT jindongli interventionalprotocolfortreatmentofcomplicationsafteresophagojejunostomyforesophagogastriccarcinoma
AT mengfeiyi interventionalprotocolfortreatmentofcomplicationsafteresophagojejunostomyforesophagogastriccarcinoma
AT zepengyu interventionalprotocolfortreatmentofcomplicationsafteresophagojejunostomyforesophagogastriccarcinoma
AT xinweihan interventionalprotocolfortreatmentofcomplicationsafteresophagojejunostomyforesophagogastriccarcinoma
AT jianzhuangren interventionalprotocolfortreatmentofcomplicationsafteresophagojejunostomyforesophagogastriccarcinoma