Evaluating the potential of phenotypic age to enhance cardiovascular risk prediction over chronological age in the UK Biobank

Evaluating the potential of phenotypic age to enhance cardiovascular risk prediction over chronological age in the UK Biobank

Abstract Phenotypic age acceleration (PhenoAgeAccel) is a novel biological indicator estimates an individual’s mortality risk. The primary aim of this study was to evaluate the association between PhenoAge and PhenoAgeAccel with incident cardiovascular diseases (CVD) in the UK Biobank cohort. We ana...

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Main Authors: Kristine J. S. Kwan, Shi-Shuai Xie, Hai-Lei Li, Xue-Guang Lin, Yi-Jie Lu, Bo Chen, Kai-Xin Ge, Shu-Ya Tang, Hui Zhang, Shuai Jiang, Jing-Dong Tang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Biological ageing
Cardiovascular disease
Phenotypic age
Risk score
Online Access:https://doi.org/10.1038/s41598-025-12495-5
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