Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity
In this report, we present a case study of how pharmacogenomics and pharmacometabolomics can be useful to characterize safety and pharmacokinetic profiles in early phase new drug development clinical trials. During conducting a first-in-human trial for a new molecular entity, we were able to determi...
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Main Authors: | Jaeseong Oh, Sojeong Yi, Namyi Gu, Dongseong Shin, Kyung-Sang Yu, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang |
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Format: | Article |
Language: | English |
Published: |
BioMed Central
2018-09-01
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Series: | Genomics & Informatics |
Subjects: | |
Online Access: | http://genominfo.org/upload/pdf/gi-2018-16-3-52.pdf |
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