Vaccination Against Androgen Receptor Splice Variants to Immunologically Target Prostate Cancer

Vaccination Against Androgen Receptor Splice Variants to Immunologically Target Prostate Cancer

<b>Background/Objectives</b>: Androgen receptor (AR) expression and signaling are critical for the progression of prostate cancer and have been the therapeutic focus of prostate cancer for over 50 years. While a variety of agents have been developed to target this axis, many of these fai...

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Bibliographic Details
Main Authors: Robert D. Marek, Selena Halabi, Mu-En Wang, Jason McBane, Junping Wei, Tao Wang, Xiao Yang, Congxiao Liu, Gangjun Lei, Herbert Kim Lyerly, Ming Chen, Timothy N. Trotter, Zachary C. Hartman
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Vaccines
Subjects:
prostate cancer
androgen receptor
vaccines
castration resistance
immune suppression
immune checkpoint inhibition
Online Access:https://www.mdpi.com/2076-393X/12/11/1273
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