Case Report: Unveiling the unexpected: a rare case of adult-type rhabdomyoma in a 9-year-old boy
Rhabdomyoma is an exceedingly rare benign soft tissue tumor of skeletal muscle origin, classified into cardiac and extracardiac types based on location. Extracardiac rhabdomyoma further includes adult, genital, and fetal types depending on the degree of differentiation. Most patients are between 40...
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2025.1451316/full |
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| author | Li Wang Shan Li Lingling Sun |
| author_facet | Li Wang Shan Li Lingling Sun |
| author_sort | Li Wang |
| collection | DOAJ |
| description | Rhabdomyoma is an exceedingly rare benign soft tissue tumor of skeletal muscle origin, classified into cardiac and extracardiac types based on location. Extracardiac rhabdomyoma further includes adult, genital, and fetal types depending on the degree of differentiation. Most patients are between 40 and 70 years old, with a mean age of 60 years and a male predominance. This case report presents a 9-year-old boy diagnosed with an oropharyngeal tumor, initially presenting with a 6-month history of a foreign body sensation in the throat, presenting as night-time snoring. Postoperative histological examination revealed adult rhabdomyoma, characterized by specific immunohistochemical and histologic traits including cytoplasmic positivity for muscle-specific Actin (MSA), Desmin, Myogenin, and MYOD1, large polygonal skeletal muscle cells and frequent extensive vacuolization. This report highlights the unusual age of presentation for this variant and underscores the need for heightened clinical awareness to ensure accurate diagnosis and effective management of such rare occurrences. |
| format | Article |
| id | doaj-art-c960d8140ad544d7b8d9e9d1b875cee1 |
| institution | Kabale University |
| issn | 2296-2360 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj-art-c960d8140ad544d7b8d9e9d1b875cee12025-02-03T06:33:29ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-02-011310.3389/fped.2025.14513161451316Case Report: Unveiling the unexpected: a rare case of adult-type rhabdomyoma in a 9-year-old boyLi Wang0Shan Li1Lingling Sun2Department of Otolaryngology, Liaocheng People's Hospital, School of Medicine, Liaocheng University, Liaocheng, Shandong, ChinaDepartment of Oncology, The Fifth People's Hospital of Jinan, Jinan, Shandong, ChinaDepartment of Otolaryngology, Liaocheng People's Hospital, Liaocheng, Shandong, ChinaRhabdomyoma is an exceedingly rare benign soft tissue tumor of skeletal muscle origin, classified into cardiac and extracardiac types based on location. Extracardiac rhabdomyoma further includes adult, genital, and fetal types depending on the degree of differentiation. Most patients are between 40 and 70 years old, with a mean age of 60 years and a male predominance. This case report presents a 9-year-old boy diagnosed with an oropharyngeal tumor, initially presenting with a 6-month history of a foreign body sensation in the throat, presenting as night-time snoring. Postoperative histological examination revealed adult rhabdomyoma, characterized by specific immunohistochemical and histologic traits including cytoplasmic positivity for muscle-specific Actin (MSA), Desmin, Myogenin, and MYOD1, large polygonal skeletal muscle cells and frequent extensive vacuolization. This report highlights the unusual age of presentation for this variant and underscores the need for heightened clinical awareness to ensure accurate diagnosis and effective management of such rare occurrences.https://www.frontiersin.org/articles/10.3389/fped.2025.1451316/fulladult-type rhabdomyomaextracardiac rhabdomyomaspharyngealchildcase report |
| spellingShingle | Li Wang Shan Li Lingling Sun Case Report: Unveiling the unexpected: a rare case of adult-type rhabdomyoma in a 9-year-old boy Frontiers in Pediatrics adult-type rhabdomyoma extracardiac rhabdomyomas pharyngeal child case report |
| title | Case Report: Unveiling the unexpected: a rare case of adult-type rhabdomyoma in a 9-year-old boy |
| title_full | Case Report: Unveiling the unexpected: a rare case of adult-type rhabdomyoma in a 9-year-old boy |
| title_fullStr | Case Report: Unveiling the unexpected: a rare case of adult-type rhabdomyoma in a 9-year-old boy |
| title_full_unstemmed | Case Report: Unveiling the unexpected: a rare case of adult-type rhabdomyoma in a 9-year-old boy |
| title_short | Case Report: Unveiling the unexpected: a rare case of adult-type rhabdomyoma in a 9-year-old boy |
| title_sort | case report unveiling the unexpected a rare case of adult type rhabdomyoma in a 9 year old boy |
| topic | adult-type rhabdomyoma extracardiac rhabdomyomas pharyngeal child case report |
| url | https://www.frontiersin.org/articles/10.3389/fped.2025.1451316/full |
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