Testosterone-Induced Effects on Lipids and Inflammation

Chronic pain has to be considered in all respects a debilitating disease and 10–20% of the world's adult population is affected by this disease. In the most general terms, pain is symptomatic of some form of dysfunction and (often) the resulting inflammatory processes in the body. In the study...

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Main Authors: Stella Vodo, Nicoletta Bechi, Anna Petroni, Carolina Muscoli, Anna Maria Aloisi
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2013/183041
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author Stella Vodo
Nicoletta Bechi
Anna Petroni
Carolina Muscoli
Anna Maria Aloisi
author_facet Stella Vodo
Nicoletta Bechi
Anna Petroni
Carolina Muscoli
Anna Maria Aloisi
author_sort Stella Vodo
collection DOAJ
description Chronic pain has to be considered in all respects a debilitating disease and 10–20% of the world's adult population is affected by this disease. In the most general terms, pain is symptomatic of some form of dysfunction and (often) the resulting inflammatory processes in the body. In the study of pain, great attention has been paid to the possible involvement of gonadal hormones, especially in recent years. In particular, testosterone, the main androgen, is thought to play a beneficial, protective role in the body. Other important elements to be related to pain, inflammation, and hormones are lipids, heterogenic molecules whose altered metabolism is often accompanied by the release of interleukins, and lipid-derived proinflammatory mediators. Here we report data on interactions often not considered in chronic pain mechanisms.
format Article
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institution Kabale University
issn 0962-9351
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language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Mediators of Inflammation
spelling doaj-art-c938701e0e8847a986a53007bda928142025-02-03T05:52:06ZengWileyMediators of Inflammation0962-93511466-18612013-01-01201310.1155/2013/183041183041Testosterone-Induced Effects on Lipids and InflammationStella Vodo0Nicoletta Bechi1Anna Petroni2Carolina Muscoli3Anna Maria Aloisi4Department of Medicine, Surgery and Neuroscience, University of Siena, Via Aldo Moro 2, 53100 Siena, ItalyDepartment of Medicine, Surgery and Neuroscience, University of Siena, Via Aldo Moro 2, 53100 Siena, ItalyDepartment of Pharmacological and Biomolecular Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, ItalyDepartment of Health Science, University of “Magna Graecia” Catanzaro and Drug Center, IRCCS San Raffaele Pisana, Via di Val Cannuta 247, 00163 Roma, ItalyDepartment of Medicine, Surgery and Neuroscience, University of Siena, Via Aldo Moro 2, 53100 Siena, ItalyChronic pain has to be considered in all respects a debilitating disease and 10–20% of the world's adult population is affected by this disease. In the most general terms, pain is symptomatic of some form of dysfunction and (often) the resulting inflammatory processes in the body. In the study of pain, great attention has been paid to the possible involvement of gonadal hormones, especially in recent years. In particular, testosterone, the main androgen, is thought to play a beneficial, protective role in the body. Other important elements to be related to pain, inflammation, and hormones are lipids, heterogenic molecules whose altered metabolism is often accompanied by the release of interleukins, and lipid-derived proinflammatory mediators. Here we report data on interactions often not considered in chronic pain mechanisms.http://dx.doi.org/10.1155/2013/183041
spellingShingle Stella Vodo
Nicoletta Bechi
Anna Petroni
Carolina Muscoli
Anna Maria Aloisi
Testosterone-Induced Effects on Lipids and Inflammation
Mediators of Inflammation
title Testosterone-Induced Effects on Lipids and Inflammation
title_full Testosterone-Induced Effects on Lipids and Inflammation
title_fullStr Testosterone-Induced Effects on Lipids and Inflammation
title_full_unstemmed Testosterone-Induced Effects on Lipids and Inflammation
title_short Testosterone-Induced Effects on Lipids and Inflammation
title_sort testosterone induced effects on lipids and inflammation
url http://dx.doi.org/10.1155/2013/183041
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AT nicolettabechi testosteroneinducedeffectsonlipidsandinflammation
AT annapetroni testosteroneinducedeffectsonlipidsandinflammation
AT carolinamuscoli testosteroneinducedeffectsonlipidsandinflammation
AT annamariaaloisi testosteroneinducedeffectsonlipidsandinflammation