Testosterone-Induced Effects on Lipids and Inflammation
Chronic pain has to be considered in all respects a debilitating disease and 10–20% of the world's adult population is affected by this disease. In the most general terms, pain is symptomatic of some form of dysfunction and (often) the resulting inflammatory processes in the body. In the study...
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Format: | Article |
Language: | English |
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Wiley
2013-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/2013/183041 |
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author | Stella Vodo Nicoletta Bechi Anna Petroni Carolina Muscoli Anna Maria Aloisi |
author_facet | Stella Vodo Nicoletta Bechi Anna Petroni Carolina Muscoli Anna Maria Aloisi |
author_sort | Stella Vodo |
collection | DOAJ |
description | Chronic pain has to be considered in all respects a debilitating disease and 10–20% of the world's adult population is affected by this disease. In the most general terms, pain is symptomatic of some form of dysfunction and (often) the resulting inflammatory processes in the body. In the study of pain, great attention has been paid to the possible involvement of gonadal hormones, especially in recent years. In particular, testosterone, the main androgen, is thought to play a beneficial, protective role in the body. Other important elements to be related to pain, inflammation, and hormones are lipids, heterogenic molecules whose altered metabolism is often accompanied by the release of interleukins, and lipid-derived proinflammatory mediators. Here we report data on interactions often not considered in chronic pain mechanisms. |
format | Article |
id | doaj-art-c938701e0e8847a986a53007bda92814 |
institution | Kabale University |
issn | 0962-9351 1466-1861 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Mediators of Inflammation |
spelling | doaj-art-c938701e0e8847a986a53007bda928142025-02-03T05:52:06ZengWileyMediators of Inflammation0962-93511466-18612013-01-01201310.1155/2013/183041183041Testosterone-Induced Effects on Lipids and InflammationStella Vodo0Nicoletta Bechi1Anna Petroni2Carolina Muscoli3Anna Maria Aloisi4Department of Medicine, Surgery and Neuroscience, University of Siena, Via Aldo Moro 2, 53100 Siena, ItalyDepartment of Medicine, Surgery and Neuroscience, University of Siena, Via Aldo Moro 2, 53100 Siena, ItalyDepartment of Pharmacological and Biomolecular Sciences, University of Milan, Via Balzaretti 9, 20133 Milan, ItalyDepartment of Health Science, University of “Magna Graecia” Catanzaro and Drug Center, IRCCS San Raffaele Pisana, Via di Val Cannuta 247, 00163 Roma, ItalyDepartment of Medicine, Surgery and Neuroscience, University of Siena, Via Aldo Moro 2, 53100 Siena, ItalyChronic pain has to be considered in all respects a debilitating disease and 10–20% of the world's adult population is affected by this disease. In the most general terms, pain is symptomatic of some form of dysfunction and (often) the resulting inflammatory processes in the body. In the study of pain, great attention has been paid to the possible involvement of gonadal hormones, especially in recent years. In particular, testosterone, the main androgen, is thought to play a beneficial, protective role in the body. Other important elements to be related to pain, inflammation, and hormones are lipids, heterogenic molecules whose altered metabolism is often accompanied by the release of interleukins, and lipid-derived proinflammatory mediators. Here we report data on interactions often not considered in chronic pain mechanisms.http://dx.doi.org/10.1155/2013/183041 |
spellingShingle | Stella Vodo Nicoletta Bechi Anna Petroni Carolina Muscoli Anna Maria Aloisi Testosterone-Induced Effects on Lipids and Inflammation Mediators of Inflammation |
title | Testosterone-Induced Effects on Lipids and Inflammation |
title_full | Testosterone-Induced Effects on Lipids and Inflammation |
title_fullStr | Testosterone-Induced Effects on Lipids and Inflammation |
title_full_unstemmed | Testosterone-Induced Effects on Lipids and Inflammation |
title_short | Testosterone-Induced Effects on Lipids and Inflammation |
title_sort | testosterone induced effects on lipids and inflammation |
url | http://dx.doi.org/10.1155/2013/183041 |
work_keys_str_mv | AT stellavodo testosteroneinducedeffectsonlipidsandinflammation AT nicolettabechi testosteroneinducedeffectsonlipidsandinflammation AT annapetroni testosteroneinducedeffectsonlipidsandinflammation AT carolinamuscoli testosteroneinducedeffectsonlipidsandinflammation AT annamariaaloisi testosteroneinducedeffectsonlipidsandinflammation |