Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient
Sugammadex is increasingly used to reverse aminosteroid neuromuscular blocking agents. Dosing is calculated based on actual body weight, even for those who are obese. We report a case where a super obese patient (BMI 58.5 kg/m2) developed asystole, following coadministration with dexmedetomidine, fo...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Anesthesiology |
| Online Access: | http://dx.doi.org/10.1155/2019/2709568 |
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| author | Michal Gajewski Sorochi Esochaghi |
| author_facet | Michal Gajewski Sorochi Esochaghi |
| author_sort | Michal Gajewski |
| collection | DOAJ |
| description | Sugammadex is increasingly used to reverse aminosteroid neuromuscular blocking agents. Dosing is calculated based on actual body weight, even for those who are obese. We report a case where a super obese patient (BMI 58.5 kg/m2) developed asystole, following coadministration with dexmedetomidine, for rapid reversal after deep blockade. Although 16mg/kg of actual body weight is recommended for prompt reversal of deep blockade, dosing adjustments may be prudent in the obese population, especially when used in conjunction with other negative chronotropic agents. |
| format | Article |
| id | doaj-art-c9011af0f8f249e2bee73f39461f5621 |
| institution | Kabale University |
| issn | 2090-6382 2090-6390 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Anesthesiology |
| spelling | doaj-art-c9011af0f8f249e2bee73f39461f56212025-02-03T06:14:18ZengWileyCase Reports in Anesthesiology2090-63822090-63902019-01-01201910.1155/2019/27095682709568Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese PatientMichal Gajewski0Sorochi Esochaghi1Department of Anesthesiology, Rutgers New Jersey Medical School, USADepartment of Anesthesiology, Rutgers New Jersey Medical School, USASugammadex is increasingly used to reverse aminosteroid neuromuscular blocking agents. Dosing is calculated based on actual body weight, even for those who are obese. We report a case where a super obese patient (BMI 58.5 kg/m2) developed asystole, following coadministration with dexmedetomidine, for rapid reversal after deep blockade. Although 16mg/kg of actual body weight is recommended for prompt reversal of deep blockade, dosing adjustments may be prudent in the obese population, especially when used in conjunction with other negative chronotropic agents.http://dx.doi.org/10.1155/2019/2709568 |
| spellingShingle | Michal Gajewski Sorochi Esochaghi Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient Case Reports in Anesthesiology |
| title | Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient |
| title_full | Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient |
| title_fullStr | Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient |
| title_full_unstemmed | Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient |
| title_short | Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient |
| title_sort | transient asystole after sugammadex administration for immediate reversal of deep blockade while on dexmedetomidine infusion in a super obese patient |
| url | http://dx.doi.org/10.1155/2019/2709568 |
| work_keys_str_mv | AT michalgajewski transientasystoleaftersugammadexadministrationforimmediatereversalofdeepblockadewhileondexmedetomidineinfusioninasuperobesepatient AT sorochiesochaghi transientasystoleaftersugammadexadministrationforimmediatereversalofdeepblockadewhileondexmedetomidineinfusioninasuperobesepatient |