Edaravone dexborneol provides neuroprotective benefits by suppressing ferroptosis in experimental intracerebral hemorrhage

Edaravone dexborneol provides neuroprotective benefits by suppressing ferroptosis in experimental intracerebral hemorrhage

Abstract Edaravone dexborneol (EDB) is widely recognized for its anti-inflammatory and antioxidant properties and is clinically applied in the treatment of acute cerebral infarction. Ferroptosis is a critical process in the pathophysiology of brain injury following intracerebral hemorrhage (ICH). Ho...

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Bibliographic Details
Main Authors: Han Li, Xiang Li, Mingzhi Li, Wenxin Li, Jinghui Wei, Yuming Huang, Haiqing Yan, Juntang Lin, Ping Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Edaravone dexborneol
Intracerebral hemorrhage
Ferroptosis
P53
GPX4
Online Access:https://doi.org/10.1038/s41598-025-99187-2
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