Focal Laser Ablation of Prostate Cancer: Definition, Needs, and Future
Current challenges and innovations in prostate cancer management concern the development of focal therapies that allow the treatment of only the cancer areas sparing the rest of the gland to minimize the potential morbidity. Among these techniques, focal laser ablation (FLA) appears as a potential c...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Advances in Urology |
| Online Access: | http://dx.doi.org/10.1155/2012/589160 |
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| _version_ | 1832550165905408000 |
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| author | Pierre Colin Serge Mordon Pierre Nevoux Mohammed Feras Marqa Adil Ouzzane Philippe Puech Gregory Bozzini Bertrand Leroux Arnauld Villers Nacim Betrouni |
| author_facet | Pierre Colin Serge Mordon Pierre Nevoux Mohammed Feras Marqa Adil Ouzzane Philippe Puech Gregory Bozzini Bertrand Leroux Arnauld Villers Nacim Betrouni |
| author_sort | Pierre Colin |
| collection | DOAJ |
| description | Current challenges and innovations in prostate cancer management concern the development of focal therapies that allow the treatment of only the cancer areas sparing the rest of the gland to minimize the potential morbidity. Among these techniques, focal laser ablation (FLA) appears as a potential candidate to reach the goal of focusing energy delivery on the identified targets. The aim of this study is to perform an up-to-date review of this new therapeutic modality. Relevant literature was identified using MEDLINE database with no language restrictions (entries: focal therapy, laser interstitial thermotherapy, prostate cancer, FLA) and by cross-referencing from previously identified studies. Precision, real-time monitoring, MRI compatibility, and low cost of integrated system are principal advantages of FLA. Feasibility and safety of this technique have been reported in phase I assays. FLA might eventually prove to be a middle ground between active surveillance and radical treatment. In conclusion, FLA may have found a role in the management of prostate cancer. However, further trials are required to demonstrate the oncologic effectiveness in the long term. |
| format | Article |
| id | doaj-art-c8f9195b06cb4cce88d41ef1b8e6d93c |
| institution | Kabale University |
| issn | 1687-6369 1687-6377 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advances in Urology |
| spelling | doaj-art-c8f9195b06cb4cce88d41ef1b8e6d93c2025-02-03T06:07:30ZengWileyAdvances in Urology1687-63691687-63772012-01-01201210.1155/2012/589160589160Focal Laser Ablation of Prostate Cancer: Definition, Needs, and FuturePierre Colin0Serge Mordon1Pierre Nevoux2Mohammed Feras Marqa3Adil Ouzzane4Philippe Puech5Gregory Bozzini6Bertrand Leroux7Arnauld Villers8Nacim Betrouni9Inserm U703, Université Lille Nord de France, CHRU Lille, 59037 Lille, FranceInserm U703, Université Lille Nord de France, CHRU Lille, 59037 Lille, FranceInserm U703, Université Lille Nord de France, CHRU Lille, 59037 Lille, FranceInserm U703, Université Lille Nord de France, CHRU Lille, 59037 Lille, FranceInserm U703, Université Lille Nord de France, CHRU Lille, 59037 Lille, FranceInserm U703, Université Lille Nord de France, CHRU Lille, 59037 Lille, FranceInserm U703, Université Lille Nord de France, CHRU Lille, 59037 Lille, FranceInserm U703, Université Lille Nord de France, CHRU Lille, 59037 Lille, FranceInserm U703, Université Lille Nord de France, CHRU Lille, 59037 Lille, FranceInserm U703, Université Lille Nord de France, CHRU Lille, 59037 Lille, FranceCurrent challenges and innovations in prostate cancer management concern the development of focal therapies that allow the treatment of only the cancer areas sparing the rest of the gland to minimize the potential morbidity. Among these techniques, focal laser ablation (FLA) appears as a potential candidate to reach the goal of focusing energy delivery on the identified targets. The aim of this study is to perform an up-to-date review of this new therapeutic modality. Relevant literature was identified using MEDLINE database with no language restrictions (entries: focal therapy, laser interstitial thermotherapy, prostate cancer, FLA) and by cross-referencing from previously identified studies. Precision, real-time monitoring, MRI compatibility, and low cost of integrated system are principal advantages of FLA. Feasibility and safety of this technique have been reported in phase I assays. FLA might eventually prove to be a middle ground between active surveillance and radical treatment. In conclusion, FLA may have found a role in the management of prostate cancer. However, further trials are required to demonstrate the oncologic effectiveness in the long term.http://dx.doi.org/10.1155/2012/589160 |
| spellingShingle | Pierre Colin Serge Mordon Pierre Nevoux Mohammed Feras Marqa Adil Ouzzane Philippe Puech Gregory Bozzini Bertrand Leroux Arnauld Villers Nacim Betrouni Focal Laser Ablation of Prostate Cancer: Definition, Needs, and Future Advances in Urology |
| title | Focal Laser Ablation of Prostate Cancer: Definition, Needs, and Future |
| title_full | Focal Laser Ablation of Prostate Cancer: Definition, Needs, and Future |
| title_fullStr | Focal Laser Ablation of Prostate Cancer: Definition, Needs, and Future |
| title_full_unstemmed | Focal Laser Ablation of Prostate Cancer: Definition, Needs, and Future |
| title_short | Focal Laser Ablation of Prostate Cancer: Definition, Needs, and Future |
| title_sort | focal laser ablation of prostate cancer definition needs and future |
| url | http://dx.doi.org/10.1155/2012/589160 |
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