A Curious Case of Sudden Refractive Change from Emmetropia to Myopia in a Post-LASIK Patient
The article discusses the potential ocular adverse effects of topiramate, an antiepileptic medication commonly used for migraine prevention. Topiramate-induced acute angle closure (TiAAC) is of particular concern as it can result in the sudden diminution of vision. The exact mechanism behind TiAAC i...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-07-01
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| Series: | Delhi Journal of Ophthalmology |
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| Online Access: | https://journals.lww.com/10.4103/DLJO.DLJO_114_23 |
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| author | Priyanka Gupta Supreet Rai Harleen Kaur Aman Goyal |
| author_facet | Priyanka Gupta Supreet Rai Harleen Kaur Aman Goyal |
| author_sort | Priyanka Gupta |
| collection | DOAJ |
| description | The article discusses the potential ocular adverse effects of topiramate, an antiepileptic medication commonly used for migraine prevention. Topiramate-induced acute angle closure (TiAAC) is of particular concern as it can result in the sudden diminution of vision. The exact mechanism behind TiAAC is uncertain, but it is thought to involve prostaglandin release, leading to ciliary body effusion. In this case, a young male who had been emmetropic postmyopic LASIK surgery presented to us with sudden onset high myopia. Detailed history revealed that the patient had been recently using topiramate. On examination, there was anterior displacement of iris lens diaphragm. In-depth investigations confirmed it to be a case of TiAAC. The patient was advised to discontinue topiramate and was put on topical steroids, intraocular pressure-lowering agents, and cycloplegics which relieved his condition within 10 days. |
| format | Article |
| id | doaj-art-c8f6bc4f9a8840e784de64c68c7f6b62 |
| institution | DOAJ |
| issn | 0972-0200 2454-2784 |
| language | English |
| publishDate | 2023-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Delhi Journal of Ophthalmology |
| spelling | doaj-art-c8f6bc4f9a8840e784de64c68c7f6b622025-08-20T03:11:07ZengWolters Kluwer Medknow PublicationsDelhi Journal of Ophthalmology0972-02002454-27842023-07-0133322322410.4103/DLJO.DLJO_114_23A Curious Case of Sudden Refractive Change from Emmetropia to Myopia in a Post-LASIK PatientPriyanka GuptaSupreet RaiHarleen KaurAman GoyalThe article discusses the potential ocular adverse effects of topiramate, an antiepileptic medication commonly used for migraine prevention. Topiramate-induced acute angle closure (TiAAC) is of particular concern as it can result in the sudden diminution of vision. The exact mechanism behind TiAAC is uncertain, but it is thought to involve prostaglandin release, leading to ciliary body effusion. In this case, a young male who had been emmetropic postmyopic LASIK surgery presented to us with sudden onset high myopia. Detailed history revealed that the patient had been recently using topiramate. On examination, there was anterior displacement of iris lens diaphragm. In-depth investigations confirmed it to be a case of TiAAC. The patient was advised to discontinue topiramate and was put on topical steroids, intraocular pressure-lowering agents, and cycloplegics which relieved his condition within 10 days.https://journals.lww.com/10.4103/DLJO.DLJO_114_23myopiasecondary angle closure glaucomatopiramate |
| spellingShingle | Priyanka Gupta Supreet Rai Harleen Kaur Aman Goyal A Curious Case of Sudden Refractive Change from Emmetropia to Myopia in a Post-LASIK Patient Delhi Journal of Ophthalmology myopia secondary angle closure glaucoma topiramate |
| title | A Curious Case of Sudden Refractive Change from Emmetropia to Myopia in a Post-LASIK Patient |
| title_full | A Curious Case of Sudden Refractive Change from Emmetropia to Myopia in a Post-LASIK Patient |
| title_fullStr | A Curious Case of Sudden Refractive Change from Emmetropia to Myopia in a Post-LASIK Patient |
| title_full_unstemmed | A Curious Case of Sudden Refractive Change from Emmetropia to Myopia in a Post-LASIK Patient |
| title_short | A Curious Case of Sudden Refractive Change from Emmetropia to Myopia in a Post-LASIK Patient |
| title_sort | curious case of sudden refractive change from emmetropia to myopia in a post lasik patient |
| topic | myopia secondary angle closure glaucoma topiramate |
| url | https://journals.lww.com/10.4103/DLJO.DLJO_114_23 |
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