Antithrombotic Therapy Does Not Jeopardize Emergency Percutaneous Nephrostomy
Objective: This study aims to evaluate the clinical outcomes of patients receiving antithrombotic (antiaggregant and anticoagulant) therapy who underwent emergency percutaneous nephrostomy (PN) for the treatment of receiving complicated upper urinary tract infection. Material and Methods: Data...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ali İhsan Taşçı
2025-02-01
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| Series: | The New Journal of Urology |
| Online Access: | https://dergipark.org.tr/en/pub/newurology/issue/90562/1603500 |
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| Summary: | Objective: This study aims to evaluate the clinical outcomes of patients receiving antithrombotic
(antiaggregant and anticoagulant) therapy who underwent emergency percutaneous nephrostomy
(PN) for the treatment of receiving complicated upper urinary tract infection.
Material and Methods: Data of consecutive patients who underwent emergency PN from January
2014 to October 2024 were retrospectively reviewed. A total of 34 patients on antithrombotic
treatment (Group 1) and 35 control group patients (Group 2) without bleeding disorders or
any antithrombotic treatment were included. Demographics, indications for PN, pre- and postprocedural
hematological, biochemical, and microbiological parameters and complications were
analyzed.
Results: The mean age was 68.65±1.49 in group 1 and 62.09±1.77 in group 2 (p = 0.006). Sex
distribution and indications for PN were comparable between groups. There was no significant
difference in emergency PN indications, grade of hydronephrosis, and PN placement sides. The
most common antithrombotic agent in group 1 was warfarin (44.1 %). Escherichia coli was the
most common bacteria isolated in both groups (55.9% vs. 48.6 % for groups 1 and 2, respectively).
No major complications were observed in either group. Blood replacement was performed in 4
and 3 patients in groups 1 and 2, respectively. Mean post-procedure Hg levels were similar in
both groups (9.53 ±1.39 vs. 9.98 ±1.18 for groups 1 and 2, respectively). No difference in median
hospital stay was observed between the groups.
Conclusion: Antithrombotic drugs pose a potential bleeding risk during PN placement. This is the
first study in the literature on PN placement in patients on antithrombotic therapy, and it shows
that the procedure can be performed with low complication rates in patients on antithrombotic
therapy. |
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| ISSN: | 3023-6940 |