Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum
Colostrum is the main external resource providing piglets with nutrients and maternal immune molecules. Astragalus polysaccharides (APS) have been used as immunopotentiators in vitro and several animal models. This study aimed to determine the effects of APS on immune factors in sow colostrum and mi...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2017/9253208 |
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| author | Lunbo Tan Ting Wei Anwen Yuan Jun He Jinhui Liu Daojun Xu Qing Yang |
| author_facet | Lunbo Tan Ting Wei Anwen Yuan Jun He Jinhui Liu Daojun Xu Qing Yang |
| author_sort | Lunbo Tan |
| collection | DOAJ |
| description | Colostrum is the main external resource providing piglets with nutrients and maternal immune molecules. Astragalus polysaccharides (APS) have been used as immunopotentiators in vitro and several animal models. This study aimed to determine the effects of APS on immune factors in sow colostrum and milk. The sow diet was supplemented with APS one week before the expected delivery date. Colostrum and milk were collected and designated as 0 h- (onset of parturition), 12 h-, and 24 h-colostrum and 36 h-milk postpartum. Samples were measured using porcine immunoglobulin (Ig) G, IgM, classical swine fever virus antibody (CSFV Ab), epidermal growth factor (EGF), and insulin-like growth factor- (IGF-) 1 ELISA Quantitation Kits. Dietary supplementation of APS significantly enhanced the presence of IgG, IgM, EGF, and IGF-1 in 0 h-colostrum (P<0.001). The blocking rates of CSFV Ab were increased in samples from APS-supplemented sow when compared to those from the matched samples without APS treatment. The results indicate that supplement of APS could improve the immune components in sow colostrum and/or milk; and status of some specific vaccination could be determined through using colostrum or early milk in sow. |
| format | Article |
| id | doaj-art-c8c054e2f23a4bfa835ebb9d2234bcc8 |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-c8c054e2f23a4bfa835ebb9d2234bcc82025-02-03T01:22:01ZengWileyJournal of Immunology Research2314-88612314-71562017-01-01201710.1155/2017/92532089253208Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow ColostrumLunbo Tan0Ting Wei1Anwen Yuan2Jun He3Jinhui Liu4Daojun Xu5Qing Yang6College of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, ChinaCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, ChinaCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, ChinaCollege of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, ChinaCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, ChinaCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, ChinaCollege of Veterinary Medicine, Hunan Agricultural University, Changsha 410128, ChinaColostrum is the main external resource providing piglets with nutrients and maternal immune molecules. Astragalus polysaccharides (APS) have been used as immunopotentiators in vitro and several animal models. This study aimed to determine the effects of APS on immune factors in sow colostrum and milk. The sow diet was supplemented with APS one week before the expected delivery date. Colostrum and milk were collected and designated as 0 h- (onset of parturition), 12 h-, and 24 h-colostrum and 36 h-milk postpartum. Samples were measured using porcine immunoglobulin (Ig) G, IgM, classical swine fever virus antibody (CSFV Ab), epidermal growth factor (EGF), and insulin-like growth factor- (IGF-) 1 ELISA Quantitation Kits. Dietary supplementation of APS significantly enhanced the presence of IgG, IgM, EGF, and IGF-1 in 0 h-colostrum (P<0.001). The blocking rates of CSFV Ab were increased in samples from APS-supplemented sow when compared to those from the matched samples without APS treatment. The results indicate that supplement of APS could improve the immune components in sow colostrum and/or milk; and status of some specific vaccination could be determined through using colostrum or early milk in sow.http://dx.doi.org/10.1155/2017/9253208 |
| spellingShingle | Lunbo Tan Ting Wei Anwen Yuan Jun He Jinhui Liu Daojun Xu Qing Yang Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum Journal of Immunology Research |
| title | Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum |
| title_full | Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum |
| title_fullStr | Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum |
| title_full_unstemmed | Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum |
| title_short | Dietary Supplementation of Astragalus Polysaccharides Enhanced Immune Components and Growth Factors EGF and IGF-1 in Sow Colostrum |
| title_sort | dietary supplementation of astragalus polysaccharides enhanced immune components and growth factors egf and igf 1 in sow colostrum |
| url | http://dx.doi.org/10.1155/2017/9253208 |
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