Cancer-associated fibroblasts, tumor and radiotherapy: interactions in the tumor micro-environment

Abstract Cancer-associated fibroblasts (CAFs) represent a group of genotypically non-malignant stromal cells in the tumor micro-environment (TME) of solid tumors that encompasses up to 80% of the tumor volume. Even though the phenotypic diversity and plasticity of CAFs complicates research, it is we...

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Bibliographic Details
Main Authors: Kris T. P. M. Raaijmakers, Gosse J. Adema, Johan Bussink, Marleen Ansems
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Experimental & Clinical Cancer Research
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Online Access:https://doi.org/10.1186/s13046-024-03251-0
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