Synchronous primary parotid tuberculosis and EBV-associated primary lymphoepithelial carcinoma
A 48-year-old gentleman presented with complaints of neck swelling in the parotid region for 2 years. Diagnostic nasal endoscopy and video laryngeal stroboscopy were normal, and positron emission tomography scan showed no other primary lesion. The lesion with tail of parotid was excised and sent for...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-04-01
|
| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ijpm.ijpm_1023_23 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850033705033138176 |
|---|---|
| author | Anandhi Anbalagan Deepti Jain Senthil Kumar Ravichander |
| author_facet | Anandhi Anbalagan Deepti Jain Senthil Kumar Ravichander |
| author_sort | Anandhi Anbalagan |
| collection | DOAJ |
| description | A 48-year-old gentleman presented with complaints of neck swelling in the parotid region for 2 years. Diagnostic nasal endoscopy and video laryngeal stroboscopy were normal, and positron emission tomography scan showed no other primary lesion. The lesion with tail of parotid was excised and sent for histopathological examination. Part of the tissue was also sent for diagnosis of tuberculosis by polymerase chain reaction (PCR) as it is a very common disease in South Asian countries. At this point, differentials considered were undifferentiated primary carcinoma, metastatic undifferentiated nasopharyngeal carcinoma, and primary lymphoepithelial carcinoma. At the same time, PCR for tuberculosis came positive with rifampicin sensitive in drug resistance testing. EBV by ISH testing came out to be positive. Final diagnosis of primary lymphoepithelial carcinoma with co-existing tuberculosis of parotid was made. The patient was started on antitubercular therapy. |
| format | Article |
| id | doaj-art-c8a3b1a3ed5e4c2e88db4a7d94b853e1 |
| institution | DOAJ |
| issn | 0377-4929 0974-5130 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj-art-c8a3b1a3ed5e4c2e88db4a7d94b853e12025-08-20T02:58:07ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302025-04-0168241842010.4103/ijpm.ijpm_1023_23Synchronous primary parotid tuberculosis and EBV-associated primary lymphoepithelial carcinomaAnandhi AnbalaganDeepti JainSenthil Kumar RavichanderA 48-year-old gentleman presented with complaints of neck swelling in the parotid region for 2 years. Diagnostic nasal endoscopy and video laryngeal stroboscopy were normal, and positron emission tomography scan showed no other primary lesion. The lesion with tail of parotid was excised and sent for histopathological examination. Part of the tissue was also sent for diagnosis of tuberculosis by polymerase chain reaction (PCR) as it is a very common disease in South Asian countries. At this point, differentials considered were undifferentiated primary carcinoma, metastatic undifferentiated nasopharyngeal carcinoma, and primary lymphoepithelial carcinoma. At the same time, PCR for tuberculosis came positive with rifampicin sensitive in drug resistance testing. EBV by ISH testing came out to be positive. Final diagnosis of primary lymphoepithelial carcinoma with co-existing tuberculosis of parotid was made. The patient was started on antitubercular therapy.https://journals.lww.com/10.4103/ijpm.ijpm_1023_23epstein barr viruslymphoepithelial carcinomaparotidsalivary glandtuberculosis |
| spellingShingle | Anandhi Anbalagan Deepti Jain Senthil Kumar Ravichander Synchronous primary parotid tuberculosis and EBV-associated primary lymphoepithelial carcinoma Indian Journal of Pathology and Microbiology epstein barr virus lymphoepithelial carcinoma parotid salivary gland tuberculosis |
| title | Synchronous primary parotid tuberculosis and EBV-associated primary lymphoepithelial carcinoma |
| title_full | Synchronous primary parotid tuberculosis and EBV-associated primary lymphoepithelial carcinoma |
| title_fullStr | Synchronous primary parotid tuberculosis and EBV-associated primary lymphoepithelial carcinoma |
| title_full_unstemmed | Synchronous primary parotid tuberculosis and EBV-associated primary lymphoepithelial carcinoma |
| title_short | Synchronous primary parotid tuberculosis and EBV-associated primary lymphoepithelial carcinoma |
| title_sort | synchronous primary parotid tuberculosis and ebv associated primary lymphoepithelial carcinoma |
| topic | epstein barr virus lymphoepithelial carcinoma parotid salivary gland tuberculosis |
| url | https://journals.lww.com/10.4103/ijpm.ijpm_1023_23 |
| work_keys_str_mv | AT anandhianbalagan synchronousprimaryparotidtuberculosisandebvassociatedprimarylymphoepithelialcarcinoma AT deeptijain synchronousprimaryparotidtuberculosisandebvassociatedprimarylymphoepithelialcarcinoma AT senthilkumarravichander synchronousprimaryparotidtuberculosisandebvassociatedprimarylymphoepithelialcarcinoma |