The Value of Repeat Clostridium difficile Toxin Testing during and after an Outbreak of C difficile-Associated Diarrhea

BACKGROUND: The recent increase in Clostridium difficile-associated diarrhea (CDAD) has led to questions about the reproducibility and sensitivity of C difficile toxin testing (CDTT). While there have been recommendations to repeat CDTT following a negative result, previous studies have failed to sh...

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Main Author: Joseph Dylewski
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2011/591239
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author Joseph Dylewski
author_facet Joseph Dylewski
author_sort Joseph Dylewski
collection DOAJ
description BACKGROUND: The recent increase in Clostridium difficile-associated diarrhea (CDAD) has led to questions about the reproducibility and sensitivity of C difficile toxin testing (CDTT). While there have been recommendations to repeat CDTT following a negative result, previous studies have failed to show a benefit. However, no studies were performed during an outbreak of CDAD. The value of repeat CDTT after an initial negative result in patients tested during and after an outbreak of CDAD is reported in the present study, as well as the reproducibility of CDTT when multiple samples are received and tested on the same day.
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spelling doaj-art-c89f82b2afcd4232827437c0923bdcc72025-02-03T01:00:40ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322011-01-01222e12e1510.1155/2011/591239The Value of Repeat Clostridium difficile Toxin Testing during and after an Outbreak of C difficile-Associated DiarrheaJoseph Dylewski0St Mary’s Hospital Center, Montreal, Quebec, CanadaBACKGROUND: The recent increase in Clostridium difficile-associated diarrhea (CDAD) has led to questions about the reproducibility and sensitivity of C difficile toxin testing (CDTT). While there have been recommendations to repeat CDTT following a negative result, previous studies have failed to show a benefit. However, no studies were performed during an outbreak of CDAD. The value of repeat CDTT after an initial negative result in patients tested during and after an outbreak of CDAD is reported in the present study, as well as the reproducibility of CDTT when multiple samples are received and tested on the same day.http://dx.doi.org/10.1155/2011/591239
spellingShingle Joseph Dylewski
The Value of Repeat Clostridium difficile Toxin Testing during and after an Outbreak of C difficile-Associated Diarrhea
Canadian Journal of Infectious Diseases and Medical Microbiology
title The Value of Repeat Clostridium difficile Toxin Testing during and after an Outbreak of C difficile-Associated Diarrhea
title_full The Value of Repeat Clostridium difficile Toxin Testing during and after an Outbreak of C difficile-Associated Diarrhea
title_fullStr The Value of Repeat Clostridium difficile Toxin Testing during and after an Outbreak of C difficile-Associated Diarrhea
title_full_unstemmed The Value of Repeat Clostridium difficile Toxin Testing during and after an Outbreak of C difficile-Associated Diarrhea
title_short The Value of Repeat Clostridium difficile Toxin Testing during and after an Outbreak of C difficile-Associated Diarrhea
title_sort value of repeat clostridium difficile toxin testing during and after an outbreak of c difficile associated diarrhea
url http://dx.doi.org/10.1155/2011/591239
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