Investigation of the synergistic effect of metformin and FX11 on PANC-1 cell lines

Investigation of the synergistic effect of metformin and FX11 on PANC-1 cell lines

Abstract Background Pancreatic cancer is among the most aggressive and malignant tumors and is a leading cause of cancer-related mortality. It is characterized by its metabolic Warburg effect and glucose dependence. Aerobic glycolysis is a key feature of metabolic reprogramming in cancer cells. This...

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Bibliographic Details
Main Authors: Melike Bayindir-Bilgic, Ezgi Duman, Deniz Turgut, Ayse Naz Kadikoylu, Nur Ekimci-Gurcan, Utku Ozbey, Aysegul Kuskucu, Omer. F. Bayrak
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Biological Research
Subjects:
Metformin
Lactate
Pancreatic neoplasms
Warburg Effect
Online Access:https://doi.org/10.1186/s40659-025-00592-8
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