CD2AP deficiency aggravates Alzheimer’s disease phenotypes and pathology through p38 MAPK activation

Abstract Background Alzheimer’s disease (AD) is the most common form of neurodegenerative disorder, which is characterized by a decline in cognitive abilities. Genome-wide association and clinicopathological studies have demonstrated that the CD2-associated protein (CD2AP) gene is one of the most im...

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Bibliographic Details
Main Authors: Yan-Yan Xue, Zhe-Sheng Zhang, Rong-Rong Lin, Hui-Fen Huang, Ke-Qing Zhu, Dian-Fu Chen, Zhi-Ying Wu, Qing-Qing Tao
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Translational Neurodegeneration
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Online Access:https://doi.org/10.1186/s40035-024-00454-5
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