The Bee Sting That Was Not: An Unusual Case of Hymenoptera Anaphylaxis Averted in a Patient Treated with Omalizumab for Asthma

This paper presents a case of hymenoptera venom anaphylaxis averted by omalizumab, a monoclonal antibody to IgE antibody. This case suggests a novel and unintentional effect of this therapy. Currently omalizumab is only FDA approved for the treatment of moderate-persistent allergic asthma. Howeve...

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Main Authors: Evelyn M. Slaughter, Nathan Boyer, Steven Bennett
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2014/138963
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author Evelyn M. Slaughter
Nathan Boyer
Steven Bennett
author_facet Evelyn M. Slaughter
Nathan Boyer
Steven Bennett
author_sort Evelyn M. Slaughter
collection DOAJ
description This paper presents a case of hymenoptera venom anaphylaxis averted by omalizumab, a monoclonal antibody to IgE antibody. This case suggests a novel and unintentional effect of this therapy. Currently omalizumab is only FDA approved for the treatment of moderate-persistent allergic asthma. However case reports, such as ours have illustrated omalizumab’s efficacy in the treatment of a myriad immunologic and allergic diseases. These outcomes have broadened the understanding of omalizumab’s complex mechanism of action.
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spelling doaj-art-c85a44096b164c31a355367ee46c042b2025-02-03T01:11:14ZengWileyCase Reports in Medicine1687-96271687-96352014-01-01201410.1155/2014/138963138963The Bee Sting That Was Not: An Unusual Case of Hymenoptera Anaphylaxis Averted in a Patient Treated with Omalizumab for AsthmaEvelyn M. Slaughter0Nathan Boyer1Steven Bennett2Department of Internal Medicine, Madigan Army Medical Center, 9040 Fitzsimmons Drive, Tacoma, WA 98431, USADepartment of Pulmonary and Critical Care Medicine, Brooke Army Medical Center, 3851 Roger Brooke Drive No. 3600, San Antonio, TX 78219, USADepartment of Pulmonary, Sleep and Critical Care Medicine, Madigan Army Medical Center, 9040 Fitzsimmons Drive, Tacoma, WA 98431, USAThis paper presents a case of hymenoptera venom anaphylaxis averted by omalizumab, a monoclonal antibody to IgE antibody. This case suggests a novel and unintentional effect of this therapy. Currently omalizumab is only FDA approved for the treatment of moderate-persistent allergic asthma. However case reports, such as ours have illustrated omalizumab’s efficacy in the treatment of a myriad immunologic and allergic diseases. These outcomes have broadened the understanding of omalizumab’s complex mechanism of action.http://dx.doi.org/10.1155/2014/138963
spellingShingle Evelyn M. Slaughter
Nathan Boyer
Steven Bennett
The Bee Sting That Was Not: An Unusual Case of Hymenoptera Anaphylaxis Averted in a Patient Treated with Omalizumab for Asthma
Case Reports in Medicine
title The Bee Sting That Was Not: An Unusual Case of Hymenoptera Anaphylaxis Averted in a Patient Treated with Omalizumab for Asthma
title_full The Bee Sting That Was Not: An Unusual Case of Hymenoptera Anaphylaxis Averted in a Patient Treated with Omalizumab for Asthma
title_fullStr The Bee Sting That Was Not: An Unusual Case of Hymenoptera Anaphylaxis Averted in a Patient Treated with Omalizumab for Asthma
title_full_unstemmed The Bee Sting That Was Not: An Unusual Case of Hymenoptera Anaphylaxis Averted in a Patient Treated with Omalizumab for Asthma
title_short The Bee Sting That Was Not: An Unusual Case of Hymenoptera Anaphylaxis Averted in a Patient Treated with Omalizumab for Asthma
title_sort bee sting that was not an unusual case of hymenoptera anaphylaxis averted in a patient treated with omalizumab for asthma
url http://dx.doi.org/10.1155/2014/138963
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