A simple tool to evaluate the effectiveness of HIV care for settings with gaps in data availability (ESTIHIV).

Many HIV clinics with poor IT-infrastructure are unable to report data on individuals in care with HIV, on antiretroviral treatment (ART) and virologically suppressed (VS), with the aim of monitoring the HIV Continuum of Care to estimate efficacy of HIV treatment programmes. We developed an estimati...

Full description

Saved in:
Bibliographic Details
Main Authors: Dorthe Raben, Marie L Jakobsen, Jamina Trajanovska, Justyna Kowalska, Anna Vassilenko, Snezana Dragas, Arjan Harxhi, Gordana Dragovic, Nadine J Jaschinski, Bastian Neesgaard, Klaus Hjorth-Larsen, Harmony Garges, Joel Gallant, Jens D Lundgren, Andrew Philips, Valentina Cambiano, Yazdan Yazdanpanah, Amanda Mocroft
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0316794
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832540209581916160
author Dorthe Raben
Marie L Jakobsen
Jamina Trajanovska
Justyna Kowalska
Anna Vassilenko
Snezana Dragas
Arjan Harxhi
Gordana Dragovic
Nadine J Jaschinski
Bastian Neesgaard
Klaus Hjorth-Larsen
Harmony Garges
Joel Gallant
Jens D Lundgren
Andrew Philips
Valentina Cambiano
Yazdan Yazdanpanah
Amanda Mocroft
author_facet Dorthe Raben
Marie L Jakobsen
Jamina Trajanovska
Justyna Kowalska
Anna Vassilenko
Snezana Dragas
Arjan Harxhi
Gordana Dragovic
Nadine J Jaschinski
Bastian Neesgaard
Klaus Hjorth-Larsen
Harmony Garges
Joel Gallant
Jens D Lundgren
Andrew Philips
Valentina Cambiano
Yazdan Yazdanpanah
Amanda Mocroft
author_sort Dorthe Raben
collection DOAJ
description Many HIV clinics with poor IT-infrastructure are unable to report data on individuals in care with HIV, on antiretroviral treatment (ART) and virologically suppressed (VS), with the aim of monitoring the HIV Continuum of Care to estimate efficacy of HIV treatment programmes. We developed an estimation-tool, ESTIHIV, and determined the minimal data required for a random sample, to produce representative estimates, with a specified level of precision, of people with HIV on ART and VS. For proof of concept, 8852 HIV positive persons from seven clinics in seven different countries, with a follow-up visit during 2017, were included. Of those, 93.8% were on ART (95% CI 93.3-94.2) and 76.7% were VS (95% CI 75.8-77.6). In 2022, we tested the tool in the RESPOND Cohort for all countries with more than 100 participants under follow-up in 2019. We included 26,426 HIV positive persons from clinics in 27 countries, 97.8% (95% CI 97.6-98.0) were on ART and 91.5% were VS (95% CI 91.2-91.8%). There was good agreement between the RESPOND country estimates of ART and VS and the estimations using a random sample calculated in ESTIHIV. With ESTIHIV, clinics can produce a reliable estimate in figures for reporting and for monitoring the effectiveness of care in their clinics.
format Article
id doaj-art-c84a36d63aed4403bc0ee3db904452ba
institution Kabale University
issn 1932-6203
language English
publishDate 2025-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj-art-c84a36d63aed4403bc0ee3db904452ba2025-02-05T05:31:54ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01201e031679410.1371/journal.pone.0316794A simple tool to evaluate the effectiveness of HIV care for settings with gaps in data availability (ESTIHIV).Dorthe RabenMarie L JakobsenJamina TrajanovskaJustyna KowalskaAnna VassilenkoSnezana DragasArjan HarxhiGordana DragovicNadine J JaschinskiBastian NeesgaardKlaus Hjorth-LarsenHarmony GargesJoel GallantJens D LundgrenAndrew PhilipsValentina CambianoYazdan YazdanpanahAmanda MocroftMany HIV clinics with poor IT-infrastructure are unable to report data on individuals in care with HIV, on antiretroviral treatment (ART) and virologically suppressed (VS), with the aim of monitoring the HIV Continuum of Care to estimate efficacy of HIV treatment programmes. We developed an estimation-tool, ESTIHIV, and determined the minimal data required for a random sample, to produce representative estimates, with a specified level of precision, of people with HIV on ART and VS. For proof of concept, 8852 HIV positive persons from seven clinics in seven different countries, with a follow-up visit during 2017, were included. Of those, 93.8% were on ART (95% CI 93.3-94.2) and 76.7% were VS (95% CI 75.8-77.6). In 2022, we tested the tool in the RESPOND Cohort for all countries with more than 100 participants under follow-up in 2019. We included 26,426 HIV positive persons from clinics in 27 countries, 97.8% (95% CI 97.6-98.0) were on ART and 91.5% were VS (95% CI 91.2-91.8%). There was good agreement between the RESPOND country estimates of ART and VS and the estimations using a random sample calculated in ESTIHIV. With ESTIHIV, clinics can produce a reliable estimate in figures for reporting and for monitoring the effectiveness of care in their clinics.https://doi.org/10.1371/journal.pone.0316794
spellingShingle Dorthe Raben
Marie L Jakobsen
Jamina Trajanovska
Justyna Kowalska
Anna Vassilenko
Snezana Dragas
Arjan Harxhi
Gordana Dragovic
Nadine J Jaschinski
Bastian Neesgaard
Klaus Hjorth-Larsen
Harmony Garges
Joel Gallant
Jens D Lundgren
Andrew Philips
Valentina Cambiano
Yazdan Yazdanpanah
Amanda Mocroft
A simple tool to evaluate the effectiveness of HIV care for settings with gaps in data availability (ESTIHIV).
PLoS ONE
title A simple tool to evaluate the effectiveness of HIV care for settings with gaps in data availability (ESTIHIV).
title_full A simple tool to evaluate the effectiveness of HIV care for settings with gaps in data availability (ESTIHIV).
title_fullStr A simple tool to evaluate the effectiveness of HIV care for settings with gaps in data availability (ESTIHIV).
title_full_unstemmed A simple tool to evaluate the effectiveness of HIV care for settings with gaps in data availability (ESTIHIV).
title_short A simple tool to evaluate the effectiveness of HIV care for settings with gaps in data availability (ESTIHIV).
title_sort simple tool to evaluate the effectiveness of hiv care for settings with gaps in data availability estihiv
url https://doi.org/10.1371/journal.pone.0316794
work_keys_str_mv AT dortheraben asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT marieljakobsen asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT jaminatrajanovska asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT justynakowalska asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT annavassilenko asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT snezanadragas asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT arjanharxhi asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT gordanadragovic asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT nadinejjaschinski asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT bastianneesgaard asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT klaushjorthlarsen asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT harmonygarges asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT joelgallant asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT jensdlundgren asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT andrewphilips asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT valentinacambiano asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT yazdanyazdanpanah asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT amandamocroft asimpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT dortheraben simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT marieljakobsen simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT jaminatrajanovska simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT justynakowalska simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT annavassilenko simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT snezanadragas simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT arjanharxhi simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT gordanadragovic simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT nadinejjaschinski simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT bastianneesgaard simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT klaushjorthlarsen simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT harmonygarges simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT joelgallant simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT jensdlundgren simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT andrewphilips simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT valentinacambiano simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT yazdanyazdanpanah simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv
AT amandamocroft simpletooltoevaluatetheeffectivenessofhivcareforsettingswithgapsindataavailabilityestihiv