The Perfect Way to Predict the Severity of Acute Pancreatitis: The Search Continues

This study was designed to determine the clinical utility of three rating scales (Ranson's, Acute Physiology And Chronic Health Evaluation [APACHE] II and Glasgow) in predicting the severity of acute pancreatitis experienced by patients known to have human immunodeficiency virus (HIV) or a...

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Main Author: Daniel C Sadowski
Format: Article
Language:English
Published: Wiley 2004-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2004/412372
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author Daniel C Sadowski
author_facet Daniel C Sadowski
author_sort Daniel C Sadowski
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description This study was designed to determine the clinical utility of three rating scales (Ranson's, Acute Physiology And Chronic Health Evaluation [APACHE] II and Glasgow) in predicting the severity of acute pancreatitis experienced by patients known to have human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS). A retrospective analysis identified 73 patients with both acute pancreatitis and HIV who had been admitted to two Canadian hospitals between 1989 and 1999. Of those 73, 11 (15%) went on to have a clinical course consistent with a diagnosis of severe pancreatitis. For the purposes of the study, severe pancreatitis was defined by the occurrence of death, intensive care unit admission, surgical intervention or significant symptomatic local complications (necrosis, abscess or pseudocyst). The authors found that the APACHE II and Ranson's scores had a sensitivity of 100% and specificities of 70% and 33% for severe pancreatitis, respectively. The Glasgow score had a statistically poorer diagnostic performance.
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spelling doaj-art-c849b0e791104fa4bf20f87b687fa67c2025-02-03T01:11:14ZengWileyCanadian Journal of Gastroenterology0835-79002004-01-0118640941010.1155/2004/412372The Perfect Way to Predict the Severity of Acute Pancreatitis: The Search ContinuesDaniel C SadowskiThis study was designed to determine the clinical utility of three rating scales (Ranson's, Acute Physiology And Chronic Health Evaluation [APACHE] II and Glasgow) in predicting the severity of acute pancreatitis experienced by patients known to have human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS). A retrospective analysis identified 73 patients with both acute pancreatitis and HIV who had been admitted to two Canadian hospitals between 1989 and 1999. Of those 73, 11 (15%) went on to have a clinical course consistent with a diagnosis of severe pancreatitis. For the purposes of the study, severe pancreatitis was defined by the occurrence of death, intensive care unit admission, surgical intervention or significant symptomatic local complications (necrosis, abscess or pseudocyst). The authors found that the APACHE II and Ranson's scores had a sensitivity of 100% and specificities of 70% and 33% for severe pancreatitis, respectively. The Glasgow score had a statistically poorer diagnostic performance.http://dx.doi.org/10.1155/2004/412372
spellingShingle Daniel C Sadowski
The Perfect Way to Predict the Severity of Acute Pancreatitis: The Search Continues
Canadian Journal of Gastroenterology
title The Perfect Way to Predict the Severity of Acute Pancreatitis: The Search Continues
title_full The Perfect Way to Predict the Severity of Acute Pancreatitis: The Search Continues
title_fullStr The Perfect Way to Predict the Severity of Acute Pancreatitis: The Search Continues
title_full_unstemmed The Perfect Way to Predict the Severity of Acute Pancreatitis: The Search Continues
title_short The Perfect Way to Predict the Severity of Acute Pancreatitis: The Search Continues
title_sort perfect way to predict the severity of acute pancreatitis the search continues
url http://dx.doi.org/10.1155/2004/412372
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