Effect of SGLT2 inhibitors on cardiac structure and function assessed by cardiac magnetic resonance: a systematic review and meta-analysis

Effect of SGLT2 inhibitors on cardiac structure and function assessed by cardiac magnetic resonance: a systematic review and meta-analysis

Abstract Background and aim Sodium-glucose cotransporter-2 inhibitors (SGLT2i) improve outcomes in patients with heart failure (HF) but underlying mechanisms remain incompletely understood. Cardiac magnetic resonance (CMR) is key in evaluating cardiac structure and function, enabling accurate assess...

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Main Authors: Isabella Leo, Nadia Salerno, Stefano Figliozzi, Angelica Cersosimo, Jessica Ielapi, Kamil Stankowski, Giandomenico Bisaccia, Santo Dellegrottaglie, Giovanni Canino, Salvatore De Rosa, Sabato Sorrentino, Chiara Bucciarelli-Ducci, Daniele Torella
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Cardiovascular Diabetology
Subjects:
Heart failure
Sodium-glucose transport protein 2
Cardiovascular magnetic resonance
Reverse cardiac remodeling
Online Access:https://doi.org/10.1186/s12933-025-02904-4
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