Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients

Introduction. The anatomic position of the sentinel lymph node is variable. The purpose of the following study was to assess the dose distribution delivered to the surgically marked sentinel lymph node site by 3D conformal radio therapy technique. Material and Method. We retrospectively analysed 70...

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Main Authors: Gerlo Witucki, Nikolaus Degregorio, Andreas Rempen, Lukas Schwentner, Dirk Bottke, Wolfgang Janni, Florian Ebner
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:International Journal of Breast Cancer
Online Access:http://dx.doi.org/10.1155/2015/539842
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author Gerlo Witucki
Nikolaus Degregorio
Andreas Rempen
Lukas Schwentner
Dirk Bottke
Wolfgang Janni
Florian Ebner
author_facet Gerlo Witucki
Nikolaus Degregorio
Andreas Rempen
Lukas Schwentner
Dirk Bottke
Wolfgang Janni
Florian Ebner
author_sort Gerlo Witucki
collection DOAJ
description Introduction. The anatomic position of the sentinel lymph node is variable. The purpose of the following study was to assess the dose distribution delivered to the surgically marked sentinel lymph node site by 3D conformal radio therapy technique. Material and Method. We retrospectively analysed 70 radiotherapy (RT) treatment plans of consecutive primary breast cancer patients with a successful, disease-free, sentinel lymph node resection. Results. In our case series the SN clip volume received a mean dose of 40.7 Gy (min 28.8 Gy/max 47.6 Gy). Conclusion. By using surgical clip markers in combination with 3D CT images our data supports the pathway of tumouricidal doses in the SN bed. The target volume should be defined by surgical clip markers and 3D CT images to give accurate dose estimations.
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id doaj-art-c83921663bd5444a8bd8508244fcee1b
institution Kabale University
issn 2090-3170
2090-3189
language English
publishDate 2015-01-01
publisher Wiley
record_format Article
series International Journal of Breast Cancer
spelling doaj-art-c83921663bd5444a8bd8508244fcee1b2025-02-03T07:23:48ZengWileyInternational Journal of Breast Cancer2090-31702090-31892015-01-01201510.1155/2015/539842539842Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer PatientsGerlo Witucki0Nikolaus Degregorio1Andreas Rempen2Lukas Schwentner3Dirk Bottke4Wolfgang Janni5Florian Ebner6Diakonieklinikum Schwäbisch Hall, Abteilung für Strahlentherapie, Diakoniestr. 10, 74523 Schwäbisch Hall, GermanyKlinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Ulm, Prittwitzerstr. 43, 89075 Ulm, GermanyDiakonieklinikum Schwäbisch Hall, Frauenklinik mit Brustzentrum und Genitalkrebszentrum, Diakoniestr. 10, 74523 Schwäbisch Hall, GermanyKlinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Ulm, Prittwitzerstr. 43, 89075 Ulm, GermanyKlinik für Strahlentherapie und Radioonkologie, Universitätsklinikum Ulm, Prittwitzerstr. 43, 89075 Ulm, GermanyKlinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Ulm, Prittwitzerstr. 43, 89075 Ulm, GermanyKlinik für Frauenheilkunde und Geburtshilfe, Universitätsklinikum Ulm, Prittwitzerstr. 43, 89075 Ulm, GermanyIntroduction. The anatomic position of the sentinel lymph node is variable. The purpose of the following study was to assess the dose distribution delivered to the surgically marked sentinel lymph node site by 3D conformal radio therapy technique. Material and Method. We retrospectively analysed 70 radiotherapy (RT) treatment plans of consecutive primary breast cancer patients with a successful, disease-free, sentinel lymph node resection. Results. In our case series the SN clip volume received a mean dose of 40.7 Gy (min 28.8 Gy/max 47.6 Gy). Conclusion. By using surgical clip markers in combination with 3D CT images our data supports the pathway of tumouricidal doses in the SN bed. The target volume should be defined by surgical clip markers and 3D CT images to give accurate dose estimations.http://dx.doi.org/10.1155/2015/539842
spellingShingle Gerlo Witucki
Nikolaus Degregorio
Andreas Rempen
Lukas Schwentner
Dirk Bottke
Wolfgang Janni
Florian Ebner
Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients
International Journal of Breast Cancer
title Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients
title_full Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients
title_fullStr Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients
title_full_unstemmed Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients
title_short Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients
title_sort evaluation of sentinel lymph node dose distribution in 3d conformal radiotherapy techniques in 67 pn0 breast cancer patients
url http://dx.doi.org/10.1155/2015/539842
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