Impulsive-Compulsive Behaviours in Belgian-Flemish Parkinson’s Disease Patients: A Questionnaire-Based Study
Background. Impulsive-compulsive behaviours (ICB) are a potentially harmful group of behavioural symptoms among the nonmotor aspects of Parkinson’s disease (PD). Objective. To develop and perform partial validation of a Belgian-Flemish version of the Questionnaire for Impulsive-Compulsive Disorders...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.1155/2019/7832487 |
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| author | Emke Maréchal Benjamin Denoiseux Ellen Thys Patrick Cras David Crosiers |
| author_facet | Emke Maréchal Benjamin Denoiseux Ellen Thys Patrick Cras David Crosiers |
| author_sort | Emke Maréchal |
| collection | DOAJ |
| description | Background. Impulsive-compulsive behaviours (ICB) are a potentially harmful group of behavioural symptoms among the nonmotor aspects of Parkinson’s disease (PD). Objective. To develop and perform partial validation of a Belgian-Flemish version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s Disease (QUIP) as a screening instrument for ICB in PD patients. Methods. Using a translation-backtranslation method, we developed a Belgian-Flemish version of the QUIP, which was subsequently completed by 88 PD patients. QUIP-positive patients were invited for a semistructured diagnostic interview. Results. A positive QUIP score for one or more ICB was observed in 37 patients (41%). In 15 patients (17%), a positive QUIP score for one or more impulse control disorders (ICD) was noted: pathological gambling in 1, hypersexuality in 8, compulsive shopping in 5, and compulsive eating in 8 patients. A positive QUIP score for punding, hobbyism, and/or walkabout was observed in 30 patients. The semistructured diagnostic interview was performed in 22 QUIP-positive patients. The diagnosis of ICB was confirmed in 6 patients, suggesting a positive predictive value of 27% for the Belgian-Flemish version of the QUIP. Conclusions. We have developed a Belgian-Flemish version of the QUIP, which can be used as a screening questionnaire for ICB in PD patients. Our data suggest that sensitivity is high, specificity is low, and validity of the questionnaire is similar to the original version. We confirm the necessity of additional clinical assessment of QUIP-positive patients to ascertain a diagnosis of ICB. |
| format | Article |
| id | doaj-art-c82b4a4e402a481d9c2a0d6b49390bdb |
| institution | Kabale University |
| issn | 2090-8083 2042-0080 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-c82b4a4e402a481d9c2a0d6b49390bdb2025-02-03T05:52:08ZengWileyParkinson's Disease2090-80832042-00802019-01-01201910.1155/2019/78324877832487Impulsive-Compulsive Behaviours in Belgian-Flemish Parkinson’s Disease Patients: A Questionnaire-Based StudyEmke Maréchal0Benjamin Denoiseux1Ellen Thys2Patrick Cras3David Crosiers4Department of Neurology, Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem, BelgiumDepartment of Neurology, Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem, BelgiumDepartment of Neurology, Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem, BelgiumDepartment of Neurology, Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem, BelgiumDepartment of Neurology, Antwerp University Hospital, Wilrijkstraat 10, 2650 Edegem, BelgiumBackground. Impulsive-compulsive behaviours (ICB) are a potentially harmful group of behavioural symptoms among the nonmotor aspects of Parkinson’s disease (PD). Objective. To develop and perform partial validation of a Belgian-Flemish version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s Disease (QUIP) as a screening instrument for ICB in PD patients. Methods. Using a translation-backtranslation method, we developed a Belgian-Flemish version of the QUIP, which was subsequently completed by 88 PD patients. QUIP-positive patients were invited for a semistructured diagnostic interview. Results. A positive QUIP score for one or more ICB was observed in 37 patients (41%). In 15 patients (17%), a positive QUIP score for one or more impulse control disorders (ICD) was noted: pathological gambling in 1, hypersexuality in 8, compulsive shopping in 5, and compulsive eating in 8 patients. A positive QUIP score for punding, hobbyism, and/or walkabout was observed in 30 patients. The semistructured diagnostic interview was performed in 22 QUIP-positive patients. The diagnosis of ICB was confirmed in 6 patients, suggesting a positive predictive value of 27% for the Belgian-Flemish version of the QUIP. Conclusions. We have developed a Belgian-Flemish version of the QUIP, which can be used as a screening questionnaire for ICB in PD patients. Our data suggest that sensitivity is high, specificity is low, and validity of the questionnaire is similar to the original version. We confirm the necessity of additional clinical assessment of QUIP-positive patients to ascertain a diagnosis of ICB.http://dx.doi.org/10.1155/2019/7832487 |
| spellingShingle | Emke Maréchal Benjamin Denoiseux Ellen Thys Patrick Cras David Crosiers Impulsive-Compulsive Behaviours in Belgian-Flemish Parkinson’s Disease Patients: A Questionnaire-Based Study Parkinson's Disease |
| title | Impulsive-Compulsive Behaviours in Belgian-Flemish Parkinson’s Disease Patients: A Questionnaire-Based Study |
| title_full | Impulsive-Compulsive Behaviours in Belgian-Flemish Parkinson’s Disease Patients: A Questionnaire-Based Study |
| title_fullStr | Impulsive-Compulsive Behaviours in Belgian-Flemish Parkinson’s Disease Patients: A Questionnaire-Based Study |
| title_full_unstemmed | Impulsive-Compulsive Behaviours in Belgian-Flemish Parkinson’s Disease Patients: A Questionnaire-Based Study |
| title_short | Impulsive-Compulsive Behaviours in Belgian-Flemish Parkinson’s Disease Patients: A Questionnaire-Based Study |
| title_sort | impulsive compulsive behaviours in belgian flemish parkinson s disease patients a questionnaire based study |
| url | http://dx.doi.org/10.1155/2019/7832487 |
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