Elderly versus young IgA nephropathy; an update on current data
IgA nephropathy (IgAN) is a common glomerular disease affecting individuals across the age spectrum. However, there are differences in the presentation and prognosis of IgAN between elderly and young adults. Elderly patients with IgAN tend to present with more severe kidney disturbances, worse basel...
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| Format: | Article |
| Language: | English |
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Society of Diabetic Nephropathy Prevention
2024-08-01
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| Series: | Journal of Nephropathology |
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| Online Access: | https://nephropathol.com/PDF/jnp-13-e25552.pdf |
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| author | Nadia Pourmohammadi Azadeh Khayyat Mohammad Ali Esmaeil Pour Maryam Ghasemi Parisa Kaviani |
| author_facet | Nadia Pourmohammadi Azadeh Khayyat Mohammad Ali Esmaeil Pour Maryam Ghasemi Parisa Kaviani |
| author_sort | Nadia Pourmohammadi |
| collection | DOAJ |
| description | IgA nephropathy (IgAN) is a common glomerular disease affecting individuals across the age spectrum. However, there are differences in the presentation and prognosis of IgAN between elderly and young adults. Elderly patients with IgAN tend to present with more severe kidney disturbances, worse baseline renal function, and a poorer prognosis compared to young adults. The Oxford classification contributes to the overall prognosis of IgAN in elderly patients by improving prognostic assessment, providing a better determinant of kidney survival, and combining histopathologic findings with clinical features. It offers a more comprehensive approach to understanding the disease course and predicting outcomes in elderly individuals with IgAN. Understanding these differences is a fundamental basis for pinpointing potential therapeutic targets to mitigate age-related renal pathology in IgAN patients. |
| format | Article |
| id | doaj-art-c828c8ffe36c43ad937cda273669e5e5 |
| institution | OA Journals |
| issn | 2251-8363 2251-8819 |
| language | English |
| publishDate | 2024-08-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Nephropathology |
| spelling | doaj-art-c828c8ffe36c43ad937cda273669e5e52025-08-20T02:30:23ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropathology2251-83632251-88192024-08-01134e25552e2555210.34172/jnp.2024.25552jnp-25552Elderly versus young IgA nephropathy; an update on current dataNadia Pourmohammadi0Azadeh Khayyat1Mohammad Ali Esmaeil Pour2Maryam Ghasemi3Parisa Kaviani4Indipendent Researcher, Mashhad, IranPathology Department of Medical College of Wisconsin, Milwaukee, WI, USAMedical College of Georgia, Augusta University, Rheumatology department, Augusta, GA, USARenal Division, Brigham and Women’s Hospital, Harvard Medical School, Boston, USAMassachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USAIgA nephropathy (IgAN) is a common glomerular disease affecting individuals across the age spectrum. However, there are differences in the presentation and prognosis of IgAN between elderly and young adults. Elderly patients with IgAN tend to present with more severe kidney disturbances, worse baseline renal function, and a poorer prognosis compared to young adults. The Oxford classification contributes to the overall prognosis of IgAN in elderly patients by improving prognostic assessment, providing a better determinant of kidney survival, and combining histopathologic findings with clinical features. It offers a more comprehensive approach to understanding the disease course and predicting outcomes in elderly individuals with IgAN. Understanding these differences is a fundamental basis for pinpointing potential therapeutic targets to mitigate age-related renal pathology in IgAN patients.https://nephropathol.com/PDF/jnp-13-e25552.pdfiga nephropathyelderlyend-stage renal diseaseacute renal failurenephrotic syndromenephrotic syndromehematuriaproteinuria |
| spellingShingle | Nadia Pourmohammadi Azadeh Khayyat Mohammad Ali Esmaeil Pour Maryam Ghasemi Parisa Kaviani Elderly versus young IgA nephropathy; an update on current data Journal of Nephropathology iga nephropathy elderly end-stage renal disease acute renal failure nephrotic syndrome nephrotic syndrome hematuria proteinuria |
| title | Elderly versus young IgA nephropathy; an update on current data |
| title_full | Elderly versus young IgA nephropathy; an update on current data |
| title_fullStr | Elderly versus young IgA nephropathy; an update on current data |
| title_full_unstemmed | Elderly versus young IgA nephropathy; an update on current data |
| title_short | Elderly versus young IgA nephropathy; an update on current data |
| title_sort | elderly versus young iga nephropathy an update on current data |
| topic | iga nephropathy elderly end-stage renal disease acute renal failure nephrotic syndrome nephrotic syndrome hematuria proteinuria |
| url | https://nephropathol.com/PDF/jnp-13-e25552.pdf |
| work_keys_str_mv | AT nadiapourmohammadi elderlyversusyoungiganephropathyanupdateoncurrentdata AT azadehkhayyat elderlyversusyoungiganephropathyanupdateoncurrentdata AT mohammadaliesmaeilpour elderlyversusyoungiganephropathyanupdateoncurrentdata AT maryamghasemi elderlyversusyoungiganephropathyanupdateoncurrentdata AT parisakaviani elderlyversusyoungiganephropathyanupdateoncurrentdata |