Preliminary Phytochemistry and Antioxidant Activities of the Ethanol Extract of Ficus abutilifolia Leaves
Medicinal plants harbor bioactive compounds utilized for addressing various health challenges. This current research focuses on the study of Ficus abutilifolia, collected from Askira Uba, Borno State, Nigeria. Ethanol was employed to extract compounds from the plant leaves. The extracts underwent q...
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Mulawarman University
2025-06-01
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| Series: | Journal of Tropical Pharmacy and Chemistry |
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| Online Access: | https://jtpc.jurnalfamul.com/index.php/jtpc/article/view/620 |
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| author | Chika Attama Luka Lawrence Ndakudu Bulama Chidama |
| author_facet | Chika Attama Luka Lawrence Ndakudu Bulama Chidama |
| author_sort | Chika Attama |
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Medicinal plants harbor bioactive compounds utilized for addressing various health challenges. This current research focuses on the study of Ficus abutilifolia, collected from Askira Uba, Borno State, Nigeria. Ethanol was employed to extract compounds from the plant leaves. The extracts underwent qualitative phytochemical screening using established procedures. The screening identified the presence of Alkaloids, Saponins, Tannins, Anthraquinones, Steroids, Glycosides, Flavonoids, reducing sugar, amino acids, and terpenoids, while Phytosterol was notably absent. The antioxidant activity of the crude extracts was assessed using two complementary test systems: 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydrogen peroxide free-radical scavenging assays, with Ascorbic acid serving as the standard. The free radical scavenging activity of the leaf crude extracts at different concentrations (2.5, 5, 7.5, and 10 µl/mL) demonstrated a concentration-dependent increase. In the DPPH method, the crude extract at a concentration of 10 ?g/mL exhibited 58.2 % antioxidant activity. Similarly, in the hydrogen peroxide radical scavenging assay, it was observed that at a concentration of 10 ?g/mL, the crude extract demonstrated an inhibition of 72.7 %. In conclusion, the ethanol extract from the plant exhibited potent inhibition of free radicals, possibly attributed to the presence of secondary metabolites.
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| format | Article |
| id | doaj-art-c81ec895e3e54500a2b9f1b4a798ff6c |
| institution | Kabale University |
| issn | 2087-7099 2407-6090 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Mulawarman University |
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| spelling | doaj-art-c81ec895e3e54500a2b9f1b4a798ff6c2025-08-20T03:28:00ZengMulawarman UniversityJournal of Tropical Pharmacy and Chemistry2087-70992407-60902025-06-019110.25026/jtpc.v9i1.620Preliminary Phytochemistry and Antioxidant Activities of the Ethanol Extract of Ficus abutilifolia LeavesChika Attama0Luka Lawrence1Ndakudu Bulama Chidama2Department of Chemistry, Faculty of Science, Modibbo Adama University, Yola, Adamawa State, NigeriaDepartment of Chemistry, Faculty of Science, Modibbo Adama University, Yola, Adamawa State, NigeriaDepartment of Chemistry, School of Sciences, Adamawa State College of Education, Hong, Nigeria Medicinal plants harbor bioactive compounds utilized for addressing various health challenges. This current research focuses on the study of Ficus abutilifolia, collected from Askira Uba, Borno State, Nigeria. Ethanol was employed to extract compounds from the plant leaves. The extracts underwent qualitative phytochemical screening using established procedures. The screening identified the presence of Alkaloids, Saponins, Tannins, Anthraquinones, Steroids, Glycosides, Flavonoids, reducing sugar, amino acids, and terpenoids, while Phytosterol was notably absent. The antioxidant activity of the crude extracts was assessed using two complementary test systems: 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydrogen peroxide free-radical scavenging assays, with Ascorbic acid serving as the standard. The free radical scavenging activity of the leaf crude extracts at different concentrations (2.5, 5, 7.5, and 10 µl/mL) demonstrated a concentration-dependent increase. In the DPPH method, the crude extract at a concentration of 10 ?g/mL exhibited 58.2 % antioxidant activity. Similarly, in the hydrogen peroxide radical scavenging assay, it was observed that at a concentration of 10 ?g/mL, the crude extract demonstrated an inhibition of 72.7 %. In conclusion, the ethanol extract from the plant exhibited potent inhibition of free radicals, possibly attributed to the presence of secondary metabolites. https://jtpc.jurnalfamul.com/index.php/jtpc/article/view/620PhytochemicalDPPHAntioxidantExtractFicus abutilifolia |
| spellingShingle | Chika Attama Luka Lawrence Ndakudu Bulama Chidama Preliminary Phytochemistry and Antioxidant Activities of the Ethanol Extract of Ficus abutilifolia Leaves Journal of Tropical Pharmacy and Chemistry Phytochemical DPPH Antioxidant Extract Ficus abutilifolia |
| title | Preliminary Phytochemistry and Antioxidant Activities of the Ethanol Extract of Ficus abutilifolia Leaves |
| title_full | Preliminary Phytochemistry and Antioxidant Activities of the Ethanol Extract of Ficus abutilifolia Leaves |
| title_fullStr | Preliminary Phytochemistry and Antioxidant Activities of the Ethanol Extract of Ficus abutilifolia Leaves |
| title_full_unstemmed | Preliminary Phytochemistry and Antioxidant Activities of the Ethanol Extract of Ficus abutilifolia Leaves |
| title_short | Preliminary Phytochemistry and Antioxidant Activities of the Ethanol Extract of Ficus abutilifolia Leaves |
| title_sort | preliminary phytochemistry and antioxidant activities of the ethanol extract of ficus abutilifolia leaves |
| topic | Phytochemical DPPH Antioxidant Extract Ficus abutilifolia |
| url | https://jtpc.jurnalfamul.com/index.php/jtpc/article/view/620 |
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