Lycopene ameliorates diabetes-induced pancreatic, hepatic, and renal damage by modulating the JAK/STAT/SOCS signaling pathway in rats

Lycopene ameliorates diabetes-induced pancreatic, hepatic, and renal damage by modulating the JAK/STAT/SOCS signaling pathway in rats

Objective(s): Emerging evidence suggests that the JAK/STAT/SOCS signaling pathway is crucial for maintaining homeostasis, and its dysregulation contributes to diabetes development. This study aimed to evaluate the roles of SOCS-1 and SOCS-3 in the pancreas, liver, and kidney and to explore the invol...

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Bibliographic Details
Main Authors: Ozlem Ozmen, Melda Şahin, Senay Topsakal, Şerife Taşan, Uğur Şahi̇n
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-04-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
apoptosis
cytokines
diabetes mellitus
inflammation
lycopene
signal transduction
Online Access:https://ijbms.mums.ac.ir/article_25548_5f629290e68b5b8a158b3b3c3a796b66.pdf
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