Potential relationship between cuproptosis and sepsis-acquired weakness: an intermediate role for mitochondria

Potential relationship between cuproptosis and sepsis-acquired weakness: an intermediate role for mitochondria

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. Skeletal muscle atrophy due to critical illness is a common phenomenon in the intensive care unit (ICU) and is referred to as ICU-acquired weakness (ICU-AW). The occurrence of ICU-AW in pat...

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Bibliographic Details
Main Authors: Luying Yang, Leiyu Xie, Min Li, Yanmei Miao, Jun Yang, Shaolin Chen, Xinglong Ma, Peng Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Physiology
Subjects:
sepsis-acquired weakness
cuproptosis
mitochondria
copper
cell death
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1520669/full
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