Sarcomatoid Renal Cell Carcinoma in an Adolescent with Sickle Cell Anaemia
Malignancies have been reported to occur in people with sickle cell disease. Renal medullary carcinoma (RMC), also tagged seventh sickle cell nephropathy, is an aggressive cancer seen almost exclusively in people with sickle cell disease with more than 160 cases reported worldwide, but only few case...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/2129450 |
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| author | H. R. Ahmad J. A. Faruk M. A. Bugaje A. Solomon M. O. A. Samaila R. M. Akuse |
| author_facet | H. R. Ahmad J. A. Faruk M. A. Bugaje A. Solomon M. O. A. Samaila R. M. Akuse |
| author_sort | H. R. Ahmad |
| collection | DOAJ |
| description | Malignancies have been reported to occur in people with sickle cell disease. Renal medullary carcinoma (RMC), also tagged seventh sickle cell nephropathy, is an aggressive cancer seen almost exclusively in people with sickle cell disease with more than 160 cases reported worldwide, but only few cases were reported in patients with sickle cell anaemia (HBSS) and from Nigeria. Sarcomatoid renal cell carcinoma is a renal tumour of any histologic variant containing foci of high-grade malignant spindle cells. We report an adolescent girl with sickle cell anaemia (HBSS) who presented with left renal tumour, histology of which confirmed a diagnosis of sarcomatoid renal cell carcinoma (sRCC). Surgical debulking and palliative care with chemotherapy were given, and she demised 10 months after. The rarity of the case and challenges of managing a cancer in the background of a chronic haematologic disorder are highlighted. |
| format | Article |
| id | doaj-art-c7e4e13eefdb4d9ba952a035131ae20a |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-c7e4e13eefdb4d9ba952a035131ae20a2025-02-03T01:00:11ZengWileyCase Reports in Oncological Medicine2090-67062090-67142017-01-01201710.1155/2017/21294502129450Sarcomatoid Renal Cell Carcinoma in an Adolescent with Sickle Cell AnaemiaH. R. Ahmad0J. A. Faruk1M. A. Bugaje2A. Solomon3M. O. A. Samaila4R. M. Akuse5Haematology/Oncology Unit, Department of Paediatrics, Ahmadu Bello University/Teaching Hospital, Zaria, NigeriaHaematology/Oncology Unit, Department of Paediatrics, Ahmadu Bello University/Teaching Hospital, Zaria, NigeriaNephrology Unit, Department of Paediatrics, Ahmadu Bello University/Teaching Hospital, Zaria, NigeriaHaematology/Oncology Unit, Department of Paediatrics, Ahmadu Bello University/Teaching Hospital, Zaria, NigeriaDepartment of Pathology, Ahmadu Bello University/Teaching Hospital, Zaria, NigeriaNephrology Unit, Department of Paediatrics, Ahmadu Bello University/Teaching Hospital, Zaria, NigeriaMalignancies have been reported to occur in people with sickle cell disease. Renal medullary carcinoma (RMC), also tagged seventh sickle cell nephropathy, is an aggressive cancer seen almost exclusively in people with sickle cell disease with more than 160 cases reported worldwide, but only few cases were reported in patients with sickle cell anaemia (HBSS) and from Nigeria. Sarcomatoid renal cell carcinoma is a renal tumour of any histologic variant containing foci of high-grade malignant spindle cells. We report an adolescent girl with sickle cell anaemia (HBSS) who presented with left renal tumour, histology of which confirmed a diagnosis of sarcomatoid renal cell carcinoma (sRCC). Surgical debulking and palliative care with chemotherapy were given, and she demised 10 months after. The rarity of the case and challenges of managing a cancer in the background of a chronic haematologic disorder are highlighted.http://dx.doi.org/10.1155/2017/2129450 |
| spellingShingle | H. R. Ahmad J. A. Faruk M. A. Bugaje A. Solomon M. O. A. Samaila R. M. Akuse Sarcomatoid Renal Cell Carcinoma in an Adolescent with Sickle Cell Anaemia Case Reports in Oncological Medicine |
| title | Sarcomatoid Renal Cell Carcinoma in an Adolescent with Sickle Cell Anaemia |
| title_full | Sarcomatoid Renal Cell Carcinoma in an Adolescent with Sickle Cell Anaemia |
| title_fullStr | Sarcomatoid Renal Cell Carcinoma in an Adolescent with Sickle Cell Anaemia |
| title_full_unstemmed | Sarcomatoid Renal Cell Carcinoma in an Adolescent with Sickle Cell Anaemia |
| title_short | Sarcomatoid Renal Cell Carcinoma in an Adolescent with Sickle Cell Anaemia |
| title_sort | sarcomatoid renal cell carcinoma in an adolescent with sickle cell anaemia |
| url | http://dx.doi.org/10.1155/2017/2129450 |
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