Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in Equines
Xylazine (1.1 mg/kg), butorphanol (0.02 mg/kg), guaifenesin 5% (20 mg/kg), and ketamine (2.2 mg/kg) combinations were able to induce short-term surgical anaesthesia for 23.33 ± 2.57 min in Spiti ponies with excellent to good muscle relaxation and analgesia. Urination and neighing was a constant feat...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Veterinary Medicine International |
| Online Access: | http://dx.doi.org/10.4061/2011/506831 |
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| author | Bhanu Partap Singh Thakur Sandeep Kumar Sharma Arvind Sharma Adarsh Kumar |
| author_facet | Bhanu Partap Singh Thakur Sandeep Kumar Sharma Arvind Sharma Adarsh Kumar |
| author_sort | Bhanu Partap Singh Thakur |
| collection | DOAJ |
| description | Xylazine (1.1 mg/kg), butorphanol (0.02 mg/kg), guaifenesin 5% (20 mg/kg), and ketamine (2.2 mg/kg) combinations were able to induce short-term surgical anaesthesia for 23.33 ± 2.57 min in Spiti ponies with excellent to good muscle relaxation and analgesia. Urination and neighing was a constant feature during recovery period. Biphasic P wave, biphasic T wave, and depressed PR segment were common electrocardiographic findings. Biochemical attributes were within physiological limits except a significant increase in ALT values during anaesthesia. The values returned to normal during recovery ruling out any renal or hepatic toxicity. Occasionally, negative T wave, notched P wave, and sinus block were noticed. It is recommended that the anaesthetic combinations xylazine-butorphanol-guaifenesin-ketamine can be safely used for short-term total intravenous anaesthesia (TIVA) in equines under field conditions. |
| format | Article |
| id | doaj-art-c7d9145a55ae4ea7b5b4c1b8a0e97bbf |
| institution | OA Journals |
| issn | 2042-0048 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Veterinary Medicine International |
| spelling | doaj-art-c7d9145a55ae4ea7b5b4c1b8a0e97bbf2025-08-20T02:19:44ZengWileyVeterinary Medicine International2042-00482011-01-01201110.4061/2011/506831506831Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in EquinesBhanu Partap Singh Thakur0Sandeep Kumar Sharma1Arvind Sharma2Adarsh Kumar3Department of Surgery and Radiology, Dr. G. C. Negi College of Veterinary & Animal Sciences, CSK Himachal Pradesh Agriculture University, Palampur (HP) 176 062, IndiaDepartment of Surgery and Radiology, Dr. G. C. Negi College of Veterinary & Animal Sciences, CSK Himachal Pradesh Agriculture University, Palampur (HP) 176 062, IndiaDepartment of Surgery and Radiology, Dr. G. C. Negi College of Veterinary & Animal Sciences, CSK Himachal Pradesh Agriculture University, Palampur (HP) 176 062, IndiaDepartment of Surgery and Radiology, Dr. G. C. Negi College of Veterinary & Animal Sciences, CSK Himachal Pradesh Agriculture University, Palampur (HP) 176 062, IndiaXylazine (1.1 mg/kg), butorphanol (0.02 mg/kg), guaifenesin 5% (20 mg/kg), and ketamine (2.2 mg/kg) combinations were able to induce short-term surgical anaesthesia for 23.33 ± 2.57 min in Spiti ponies with excellent to good muscle relaxation and analgesia. Urination and neighing was a constant feature during recovery period. Biphasic P wave, biphasic T wave, and depressed PR segment were common electrocardiographic findings. Biochemical attributes were within physiological limits except a significant increase in ALT values during anaesthesia. The values returned to normal during recovery ruling out any renal or hepatic toxicity. Occasionally, negative T wave, notched P wave, and sinus block were noticed. It is recommended that the anaesthetic combinations xylazine-butorphanol-guaifenesin-ketamine can be safely used for short-term total intravenous anaesthesia (TIVA) in equines under field conditions.http://dx.doi.org/10.4061/2011/506831 |
| spellingShingle | Bhanu Partap Singh Thakur Sandeep Kumar Sharma Arvind Sharma Adarsh Kumar Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in Equines Veterinary Medicine International |
| title | Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in Equines |
| title_full | Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in Equines |
| title_fullStr | Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in Equines |
| title_full_unstemmed | Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in Equines |
| title_short | Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in Equines |
| title_sort | clinical evaluation of xylazine butorphanol guaifenesin ketamine as short term tiva in equines |
| url | http://dx.doi.org/10.4061/2011/506831 |
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