Megapneumonia Coinfection: pneumococcus, Mycoplasma pneumoniae, and Metapneumovirus
We report a young girl who died of Streptococcus pneumoniae 19A pneumonia, septic shock, and hemolytic uremic syndrome despite prior pneumococcal vaccination, appropriate antibiotics, and aggressive intensive care support. Serotype 19A is not covered by the 7- or 10-valent pneumococcal vaccines. Myc...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/310104 |
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| _version_ | 1832545468695969792 |
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| author | Kam Lun Hon Margaret Ip Winnie Chiu Wing Chu William Wong |
| author_facet | Kam Lun Hon Margaret Ip Winnie Chiu Wing Chu William Wong |
| author_sort | Kam Lun Hon |
| collection | DOAJ |
| description | We report a young girl who died of Streptococcus pneumoniae 19A pneumonia, septic shock, and hemolytic uremic syndrome despite prior pneumococcal vaccination, appropriate antibiotics, and aggressive intensive care support. Serotype 19A is not covered by the 7- or 10-valent pneumococcal vaccines. Mycoplasma pneumoniae and metapneumovirus were simultaneously detected by PCR in the nasopharyngeal and tracheal aspirates. The pneumococcus is penicillin sensitive. Although infections with each of these pathogens alone are typically mild, this case highlights that co-infection with the triple respiratory pathogens possibly contributed to the fatal outcome of this child. Also, the new policy in Hong Kong to use PCV13 may help prevent further cases of serotype 19A infections. |
| format | Article |
| id | doaj-art-c7d1e47835cf43e19a1b62a94cdbaad9 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-c7d1e47835cf43e19a1b62a94cdbaad92025-02-03T07:25:44ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/310104310104Megapneumonia Coinfection: pneumococcus, Mycoplasma pneumoniae, and MetapneumovirusKam Lun Hon0Margaret Ip1Winnie Chiu Wing Chu2William Wong3Department of Paediatrics, The Chinese University of Hong Kong, 6/F Clinical Sciences Building, Prince of Wales Hospital, Shatin, Hong KongDepartment of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong KongDepartment of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong KongDepartment of Paediatrics, The Chinese University of Hong Kong, 6/F Clinical Sciences Building, Prince of Wales Hospital, Shatin, Hong KongWe report a young girl who died of Streptococcus pneumoniae 19A pneumonia, septic shock, and hemolytic uremic syndrome despite prior pneumococcal vaccination, appropriate antibiotics, and aggressive intensive care support. Serotype 19A is not covered by the 7- or 10-valent pneumococcal vaccines. Mycoplasma pneumoniae and metapneumovirus were simultaneously detected by PCR in the nasopharyngeal and tracheal aspirates. The pneumococcus is penicillin sensitive. Although infections with each of these pathogens alone are typically mild, this case highlights that co-infection with the triple respiratory pathogens possibly contributed to the fatal outcome of this child. Also, the new policy in Hong Kong to use PCV13 may help prevent further cases of serotype 19A infections.http://dx.doi.org/10.1155/2012/310104 |
| spellingShingle | Kam Lun Hon Margaret Ip Winnie Chiu Wing Chu William Wong Megapneumonia Coinfection: pneumococcus, Mycoplasma pneumoniae, and Metapneumovirus Case Reports in Medicine |
| title | Megapneumonia Coinfection: pneumococcus, Mycoplasma pneumoniae, and Metapneumovirus |
| title_full | Megapneumonia Coinfection: pneumococcus, Mycoplasma pneumoniae, and Metapneumovirus |
| title_fullStr | Megapneumonia Coinfection: pneumococcus, Mycoplasma pneumoniae, and Metapneumovirus |
| title_full_unstemmed | Megapneumonia Coinfection: pneumococcus, Mycoplasma pneumoniae, and Metapneumovirus |
| title_short | Megapneumonia Coinfection: pneumococcus, Mycoplasma pneumoniae, and Metapneumovirus |
| title_sort | megapneumonia coinfection pneumococcus mycoplasma pneumoniae and metapneumovirus |
| url | http://dx.doi.org/10.1155/2012/310104 |
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