Cardiovascular Disease Multimorbidity and Decreased Health‐Related Quality of Life in Haiti: A Cross‐Sectional Study
Background Multimorbidity is increasingly prevalent in lower‐ and middle‐income countries. Health‐related quality of life (HRQOL) has been inversely associated with multimorbidity but is understudied in lower‐ and middle‐income countries. We report cardiovascular disease (CVD) multimorbidity in Hait...
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Wiley
2025-02-01
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| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
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| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.124.036139 |
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| author | Shalom Sabwa Vanessa Rouzier Rodney Sufra Reichling St. Sauveur Nour Mourra Rehana Rasul Joseph Inddy Lily D. Yan Madeline Sterling Laura Pinheiro Marie Deschamps Jean William Pape Margaret L. McNairy |
| author_facet | Shalom Sabwa Vanessa Rouzier Rodney Sufra Reichling St. Sauveur Nour Mourra Rehana Rasul Joseph Inddy Lily D. Yan Madeline Sterling Laura Pinheiro Marie Deschamps Jean William Pape Margaret L. McNairy |
| author_sort | Shalom Sabwa |
| collection | DOAJ |
| description | Background Multimorbidity is increasingly prevalent in lower‐ and middle‐income countries. Health‐related quality of life (HRQOL) has been inversely associated with multimorbidity but is understudied in lower‐ and middle‐income countries. We report cardiovascular disease (CVD) multimorbidity in Haiti and its association with HRQOL. Methods and Results We used data from the Haiti CVD Cohort, a population‐based longitudinal cohort of adults. CVD multimorbidity was 2+ CVD risk factors/diseases at enrollment. HRQOL was measured using the Short Form‐12, yielding physical component summary/mental component summary scores between 0 and 100, with higher scores indicating better HRQOL. We used linear regressions to assess the association between CVD multimorbidity and HRQOL and individual CVD comorbidities and HRQOL. Additionally, we examined sex and education as potential effect modifiers. Among 2,996 participants, the median age was 40 years (interquartile range [IQR], 27–55), 58.0% were women, and 70.3% earned <1 US dollar per day. CVD multimorbidity prevalence was 24.1%; compared with those without CVD multimorbidity, those with CVD multimorbidity were older (median age, 56.0 years [IQR, 47.0–53.0]) and women (70.5%). Adjusted models revealed CVD multimorbidity was inversely related to physical component summary (−2.7 [95% CI, −3.8 to −1.6]) and mental component summary (−1.0 [95% CI, −1.8 to −0.2]). Heart failure and hypertension showed the strongest CVD morbidities associated with poor HRQOL. In the interaction analysis, among men, CVD multimorbidity was associated with a 4.3‐point lower physical component summary score. Among those with less education, CVD multimorbidity was associated with a 4.6‐point lower physical component summary score than no CVD multimorbidity. Conclusions Our data are among the first to describe HRQOL data with high CVD multimorbidity in a young population in urban Haiti, and CVD multimorbidity was associated with decreased HRQOL. Registration URL: https://www.clinicaltrials.gov; Unique identifier: NCT03892265. |
| format | Article |
| id | doaj-art-c7c90a9de28f4aafb95de20ad1951147 |
| institution | Kabale University |
| issn | 2047-9980 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj-art-c7c90a9de28f4aafb95de20ad19511472025-02-04T11:00:01ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802025-02-0114310.1161/JAHA.124.036139Cardiovascular Disease Multimorbidity and Decreased Health‐Related Quality of Life in Haiti: A Cross‐Sectional StudyShalom Sabwa0Vanessa Rouzier1Rodney Sufra2Reichling St. Sauveur3Nour Mourra4Rehana Rasul5Joseph Inddy6Lily D. Yan7Madeline Sterling8Laura Pinheiro9Marie Deschamps10Jean William Pape11Margaret L. McNairy12Department of Epidemiology Emory University Rollins School of Public Health Atlanta GACenter for Global Health Weill Cornell Medicine New York NYHaitian Group for the Study of Kaposi’s Sarcoma and Opportunistic Infections (GHESKIO) Port‐au‐Prince HaitiHaitian Group for the Study of Kaposi’s Sarcoma and Opportunistic Infections (GHESKIO) Port‐au‐Prince HaitiCenter for Global Health Weill Cornell Medicine New York NYDepartment of Epidemiology and Biostatistics, Graduate School of Public Health and Health Policy City University of New York New York NYHaitian Group for the Study of Kaposi’s Sarcoma and Opportunistic Infections (GHESKIO) Port‐au‐Prince HaitiCenter for Global Health Weill Cornell Medicine New York NYDivision of General Internal Medicine, Department of Medicine Weill Cornell Medicine New York NYDivision of General Internal Medicine, Department of Medicine Weill Cornell Medicine New York NYHaitian Group for the Study of Kaposi’s Sarcoma and Opportunistic Infections (GHESKIO) Port‐au‐Prince HaitiCenter for Global Health Weill Cornell Medicine New York NYCenter for Global Health Weill Cornell Medicine New York NYBackground Multimorbidity is increasingly prevalent in lower‐ and middle‐income countries. Health‐related quality of life (HRQOL) has been inversely associated with multimorbidity but is understudied in lower‐ and middle‐income countries. We report cardiovascular disease (CVD) multimorbidity in Haiti and its association with HRQOL. Methods and Results We used data from the Haiti CVD Cohort, a population‐based longitudinal cohort of adults. CVD multimorbidity was 2+ CVD risk factors/diseases at enrollment. HRQOL was measured using the Short Form‐12, yielding physical component summary/mental component summary scores between 0 and 100, with higher scores indicating better HRQOL. We used linear regressions to assess the association between CVD multimorbidity and HRQOL and individual CVD comorbidities and HRQOL. Additionally, we examined sex and education as potential effect modifiers. Among 2,996 participants, the median age was 40 years (interquartile range [IQR], 27–55), 58.0% were women, and 70.3% earned <1 US dollar per day. CVD multimorbidity prevalence was 24.1%; compared with those without CVD multimorbidity, those with CVD multimorbidity were older (median age, 56.0 years [IQR, 47.0–53.0]) and women (70.5%). Adjusted models revealed CVD multimorbidity was inversely related to physical component summary (−2.7 [95% CI, −3.8 to −1.6]) and mental component summary (−1.0 [95% CI, −1.8 to −0.2]). Heart failure and hypertension showed the strongest CVD morbidities associated with poor HRQOL. In the interaction analysis, among men, CVD multimorbidity was associated with a 4.3‐point lower physical component summary score. Among those with less education, CVD multimorbidity was associated with a 4.6‐point lower physical component summary score than no CVD multimorbidity. Conclusions Our data are among the first to describe HRQOL data with high CVD multimorbidity in a young population in urban Haiti, and CVD multimorbidity was associated with decreased HRQOL. Registration URL: https://www.clinicaltrials.gov; Unique identifier: NCT03892265.https://www.ahajournals.org/doi/10.1161/JAHA.124.036139cardiovascular diseaseglobal healthmultimorbidity |
| spellingShingle | Shalom Sabwa Vanessa Rouzier Rodney Sufra Reichling St. Sauveur Nour Mourra Rehana Rasul Joseph Inddy Lily D. Yan Madeline Sterling Laura Pinheiro Marie Deschamps Jean William Pape Margaret L. McNairy Cardiovascular Disease Multimorbidity and Decreased Health‐Related Quality of Life in Haiti: A Cross‐Sectional Study Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease cardiovascular disease global health multimorbidity |
| title | Cardiovascular Disease Multimorbidity and Decreased Health‐Related Quality of Life in Haiti: A Cross‐Sectional Study |
| title_full | Cardiovascular Disease Multimorbidity and Decreased Health‐Related Quality of Life in Haiti: A Cross‐Sectional Study |
| title_fullStr | Cardiovascular Disease Multimorbidity and Decreased Health‐Related Quality of Life in Haiti: A Cross‐Sectional Study |
| title_full_unstemmed | Cardiovascular Disease Multimorbidity and Decreased Health‐Related Quality of Life in Haiti: A Cross‐Sectional Study |
| title_short | Cardiovascular Disease Multimorbidity and Decreased Health‐Related Quality of Life in Haiti: A Cross‐Sectional Study |
| title_sort | cardiovascular disease multimorbidity and decreased health related quality of life in haiti a cross sectional study |
| topic | cardiovascular disease global health multimorbidity |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.124.036139 |
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