TIMM8B promotes oxidative phosphorylation and glycolysis by inhibiting the mtROS/ASK1/JNK signaling pathway in ovarian cancer

TIMM8B promotes oxidative phosphorylation and glycolysis by inhibiting the mtROS/ASK1/JNK signaling pathway in ovarian cancer

Abstract Background Ovarian cancer is a complicated and heterogeneous disease. In this study, we investigated the functional significance of the gene TIMM8B, which is differentially expressed in ovarian cancer to better understand the molecular processes involved in the development of this disease....

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Bibliographic Details
Main Authors: Yue Jia, Jiaqian Liao, Xiangqun Yang, Hongyan Hu, Wentao Zhao, Liufang Zhao, Conghui Ai, Yuanbo Xue, Shufen Tan, Yi Zhang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Biology Direct
Subjects:
TIMM8B
Oxidative phosphorylation
Glycolysis
MtROS/ASK1/JNK signaling pathway
Online Access:https://doi.org/10.1186/s13062-025-00663-6
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