New insights into the effects of Aspergillus oryzae administration during the transition period in Bubalus bubalis
The transition period is often associated with metabolic disorders in Bubalus bubalis. We examined the potential effect of Aspergillus oryzae (ASG) on blood biochemistry, adaptive immunity, milk yield and composition, dry matter intake, inflammation markers, and oxidative stress in buffalo cows. Thi...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Italian Journal of Animal Science |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/1828051X.2025.2453552 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832584751189327872 |
|---|---|
| author | Sameh A. Abdelnour Walaa M. Essawi Nasser Ghanem Ibrahim T. El-Ratel Abdel-Wahab A. Abdel-Warith Elsayed M. Younis Ahmed N. F. Neamat-Allah Shimaa A. Amer Simon J. Davies Ali Ali El-Raghi |
| author_facet | Sameh A. Abdelnour Walaa M. Essawi Nasser Ghanem Ibrahim T. El-Ratel Abdel-Wahab A. Abdel-Warith Elsayed M. Younis Ahmed N. F. Neamat-Allah Shimaa A. Amer Simon J. Davies Ali Ali El-Raghi |
| author_sort | Sameh A. Abdelnour |
| collection | DOAJ |
| description | The transition period is often associated with metabolic disorders in Bubalus bubalis. We examined the potential effect of Aspergillus oryzae (ASG) on blood biochemistry, adaptive immunity, milk yield and composition, dry matter intake, inflammation markers, and oxidative stress in buffalo cows. Thirty buffalo cows were divided into two homogeneous experimental groups (15 buffalo cows in each group) from 3 weeks pre-partum to 3 weeks post-partum. The first group received the basal diet and served as a control, while the second group was orally administered with 5 g of ASG per head per day. ASG treatment significantly improved liver and kidney functions. The concentration of haptoglobin, tumour necrosis factor-alpha (TNF-α), and Malondialdehyde (MDA) was significantly lower in the treated group (4.42 mg/dl, 68.89 pg/ml, 3.46 nmol, respectively) than in the control group (8.29 mg/dl, 83 pg/ml, 6.23 nmol, respectively). At the same time, the levels of catalase (CAT), glutathione peroxidase (GPx), immunoglobulin M, and G were significantly higher. Regarding energy metabolism, the ASG supplementation significantly increased total cholesterol, triglycerides, and high-density lipoprotein compared to the control group. Meanwhile, beta-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA), and somatic cell counts in milk (SCC) were significantly reduced by ASG supplementation. The daily milk yield and its composition were significantly increased by the ASG supplementation (p < 0.001). In conclusion, the oral administration of 5 g ASG/ head/ day during the transition period improved milk yield, health status, and adaptive immunity in lactating buffalo cows. Additionally, it decreased inflammation and oxidative stress pathways. |
| format | Article |
| id | doaj-art-c7565ea633cd404a99cd3cfb9d76d0db |
| institution | Kabale University |
| issn | 1594-4077 1828-051X |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Italian Journal of Animal Science |
| spelling | doaj-art-c7565ea633cd404a99cd3cfb9d76d0db2025-01-27T11:59:10ZengTaylor & Francis GroupItalian Journal of Animal Science1594-40771828-051X2025-12-0124130932310.1080/1828051X.2025.24535522453552New insights into the effects of Aspergillus oryzae administration during the transition period in Bubalus bubalisSameh A. Abdelnour0Walaa M. Essawi1Nasser Ghanem2Ibrahim T. El-Ratel3Abdel-Wahab A. Abdel-Warith4Elsayed M. Younis5Ahmed N. F. Neamat-Allah6Shimaa A. Amer7Simon J. Davies8Ali Ali El-Raghi9Department of Animal Production, Faculty of Agriculture, Zagazig UniversityDepartment of Theriogenology, Faculty of Veterinary Medicine, Aswan UniversityDepartment of Animal Production, Faculty of Agriculture, Cairo UniversityDepartment of Animal, Poultry and Fish Production, Faculty of Agriculture, Damietta UniversityDepartment of Zoology, College of Science, King Saud UniversityDepartment of Zoology, College of Science, King Saud UniversityDepartment of Clinical Pathology, Faculty of Veterinary Medicine, Zagazig UniversityDepartment of Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, Zagazig UniversityAquaculture Nutrition Research Unit ANRU, Carna Research Station, Ryan Institute, College of Science and Engineering, University of GalwayDepartment of Animal, Poultry and Fish Production, Faculty of Agriculture, Damietta UniversityThe transition period is often associated with metabolic disorders in Bubalus bubalis. We examined the potential effect of Aspergillus oryzae (ASG) on blood biochemistry, adaptive immunity, milk yield and composition, dry matter intake, inflammation markers, and oxidative stress in buffalo cows. Thirty buffalo cows were divided into two homogeneous experimental groups (15 buffalo cows in each group) from 3 weeks pre-partum to 3 weeks post-partum. The first group received the basal diet and served as a control, while the second group was orally administered with 5 g of ASG per head per day. ASG treatment significantly improved liver and kidney functions. The concentration of haptoglobin, tumour necrosis factor-alpha (TNF-α), and Malondialdehyde (MDA) was significantly lower in the treated group (4.42 mg/dl, 68.89 pg/ml, 3.46 nmol, respectively) than in the control group (8.29 mg/dl, 83 pg/ml, 6.23 nmol, respectively). At the same time, the levels of catalase (CAT), glutathione peroxidase (GPx), immunoglobulin M, and G were significantly higher. Regarding energy metabolism, the ASG supplementation significantly increased total cholesterol, triglycerides, and high-density lipoprotein compared to the control group. Meanwhile, beta-hydroxybutyrate (BHB), non-esterified fatty acids (NEFA), and somatic cell counts in milk (SCC) were significantly reduced by ASG supplementation. The daily milk yield and its composition were significantly increased by the ASG supplementation (p < 0.001). In conclusion, the oral administration of 5 g ASG/ head/ day during the transition period improved milk yield, health status, and adaptive immunity in lactating buffalo cows. Additionally, it decreased inflammation and oxidative stress pathways.http://dx.doi.org/10.1080/1828051X.2025.2453552antioxidantaspergillus oryzaebuffalo cowstransition periodimmunity |
| spellingShingle | Sameh A. Abdelnour Walaa M. Essawi Nasser Ghanem Ibrahim T. El-Ratel Abdel-Wahab A. Abdel-Warith Elsayed M. Younis Ahmed N. F. Neamat-Allah Shimaa A. Amer Simon J. Davies Ali Ali El-Raghi New insights into the effects of Aspergillus oryzae administration during the transition period in Bubalus bubalis Italian Journal of Animal Science antioxidant aspergillus oryzae buffalo cows transition period immunity |
| title | New insights into the effects of Aspergillus oryzae administration during the transition period in Bubalus bubalis |
| title_full | New insights into the effects of Aspergillus oryzae administration during the transition period in Bubalus bubalis |
| title_fullStr | New insights into the effects of Aspergillus oryzae administration during the transition period in Bubalus bubalis |
| title_full_unstemmed | New insights into the effects of Aspergillus oryzae administration during the transition period in Bubalus bubalis |
| title_short | New insights into the effects of Aspergillus oryzae administration during the transition period in Bubalus bubalis |
| title_sort | new insights into the effects of aspergillus oryzae administration during the transition period in bubalus bubalis |
| topic | antioxidant aspergillus oryzae buffalo cows transition period immunity |
| url | http://dx.doi.org/10.1080/1828051X.2025.2453552 |
| work_keys_str_mv | AT samehaabdelnour newinsightsintotheeffectsofaspergillusoryzaeadministrationduringthetransitionperiodinbubalusbubalis AT walaamessawi newinsightsintotheeffectsofaspergillusoryzaeadministrationduringthetransitionperiodinbubalusbubalis AT nasserghanem newinsightsintotheeffectsofaspergillusoryzaeadministrationduringthetransitionperiodinbubalusbubalis AT ibrahimtelratel newinsightsintotheeffectsofaspergillusoryzaeadministrationduringthetransitionperiodinbubalusbubalis AT abdelwahabaabdelwarith newinsightsintotheeffectsofaspergillusoryzaeadministrationduringthetransitionperiodinbubalusbubalis AT elsayedmyounis newinsightsintotheeffectsofaspergillusoryzaeadministrationduringthetransitionperiodinbubalusbubalis AT ahmednfneamatallah newinsightsintotheeffectsofaspergillusoryzaeadministrationduringthetransitionperiodinbubalusbubalis AT shimaaaamer newinsightsintotheeffectsofaspergillusoryzaeadministrationduringthetransitionperiodinbubalusbubalis AT simonjdavies newinsightsintotheeffectsofaspergillusoryzaeadministrationduringthetransitionperiodinbubalusbubalis AT alialielraghi newinsightsintotheeffectsofaspergillusoryzaeadministrationduringthetransitionperiodinbubalusbubalis |