Endoperoxides as Antimalarials: Development, Structural Diversity, and Pharmacodynamic Aspects of 1,2,4,5-Tetraoxane-Based Structural Scaffolds

Endoperoxides as Antimalarials: Development, Structural Diversity, and Pharmacodynamic Aspects of 1,2,4,5-Tetraoxane-Based Structural Scaffolds

Saved in:

Bibliographic Details
Main Authors:	Upendra Kumar Patel, Alka Alka, Alka Agarwal
Format:	Article
Language:	English
Published:	Georg Thieme Verlag KG 2025-01-01
Series:	SynOpen
Subjects:	artemisinin endoperoxide cerebral malaria sesquiterpene central nervous system (CNS) 1,2,4,5-tetroxane 1,2,4,5-tetraoxane
Online Access:	http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1775432
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Synthesis and crystal structure of 2,2,2-trichloroethyl N-{4-[6-(1-hydroxyethyl)-1,2,4,5-tetrazin-3-yl]benzyl}carbamate
by: J. Voss, et al.
Published: (2025-02-01)

Synthesis and Characteristics of 1,2,4,5-Tetrazines for Using as High Energy Density Materials (HEDMs)
by: Sebastian Górecki, et al.
Published: (2025-01-01)

Strengthening Families: Knowledge of Parenting and Child Development
by: David C. Diehl, et al.
Published: (2011-12-01)

Southern Highbush Blueberry Cultivars from the University of Florida
by: Jeffrey G. Williamson, et al.
Published: (2014-06-01)

Strengthening Families: Knowledge of Parenting and Child Development
by: David C. Diehl, et al.
Published: (2011-12-01)

Southern Highbush Blueberry Cultivars from the University of Florida
by: Jeffrey G. Williamson, et al.
Published: (2014-06-01)

The Expression Pattern of Prostaglandin-Endoperoxide Synthase-2 in Immature Oocytes and Surrounding Cumulus Cells May Explain A Disrupted Oocyte Maturation Process
by: Goktan Kuspinar, et al.
Published: (2021-12-01)

Allegorie as argument. Galasiërs 4:21-5:1 in retoriese perspektief
by: D. F. Tolmie
Published: (2002-12-01)

Targets of influenza human T-cell response are mostly conserved in H5N1
by: John Sidney, et al.
Published: (2025-02-01)

Synthesis of thiophene and N-substituted thieno[3,2-d] pyrimidine derivatives as potent antitumor and antibacterial agents
by: Hafez Hend N., et al.
Published: (2017-09-01)

Reverse-Phase Chromatographic Determination and Intrinsic Stability Behavior of 5-[(4-Chlorophenoxy)Methyl]-1,3,4-Oxadiazole-2-Thiol
by: Shehzadi Naureen, et al.
Published: (2018-12-01)

Chemical Composition and Antibacterial Activity of the Essential Oil from Leaves of Zanthoxylum kleinii (R.S. Cowan) P.G. Waterman (Rutaceae)
by: Karine Amorim Fladzinski, et al.
Published: (2025-02-01)

MicroRNA-32-5p promotes the proliferation and metastasis of gastric cancer cells
by: Chao Sun, et al.
Published: (2025-01-01)

C5a/C5aR regulates Th1/Th2 imbalance in sepsis-associated lung injury by promoting neutrophil activation to increase PAD4 expression
by: Zhenbing Lu, et al.
Published: (2025-12-01)

Synthesis and characterization of some novel 1,2,4-triazoles, 1,3,4-thiadiazoles and Schiff bases incorporating imidazole moiety as potential antimicrobial agents
by: Aouad Mohamed Reda, et al.
Published: (2015-06-01)

Unraveling the heterogeneity of WHO grade 4 gliomas: insights from clinical, imaging, and molecular characterization
by: Haihui Jiang, et al.
Published: (2025-02-01)

Green ultrasound-assisted three-component click synthesis of novel 1H-1,2,3-triazole carrying benzothiazoles and fluorinated-1,2,4-triazole conjugates and their antimicrobial evaluation
by: Rezki Nadjet, et al.
Published: (2017-09-01)

Enhanced electrochemical performances of LiNi0.5Mn1.5O4 by surface modification with Cu nanoparticles
by: Zhao G., et al.
Published: (2017-01-01)

Design, synthesis, SAR and ADMET analyses of the novel class of synthetic 7-amino[1,2,5]oxadiazolo[3,4-b]pyridine-6-carboxylate derivatives with vasorelaxant activity
by: Anatolii Varenyk, et al.
Published: (2025-01-01)

Synthesis, Characterisation, Theoretical NMR Calculations and Crystal Structure of the 3-methyl-1H-1,2,4?4-triazole-5-amine acetate
by: Patricia Saraiva Vilas Boas Almeida, et al.
Published: (2022-09-01)

Balıkesir şehir merkezinde hava kirliliği seviyelerinin zamansal ve mekansal analizleri
by: İhsan Çıldır, et al.
Published: (2022-06-01)

High throughput microwell spectrophotometric assay for olmesartan medoxomil in tablets based on its charge-transfer reaction with DDQ
by: Darwish Ibrahim A., et al.
Published: (2014-03-01)

Design, synthesis, and anti-inflammatory activity of 2H-1,4-benzoxazin-3(4H)-one derivatives modified with 1,2,3-triazole in LPS-induced BV-2 cells
by: Xixi Hou, et al.
Published: (2025-01-01)

Recurrent pregnancy loss: etiology, pathophysiology, diagnosis and treatment
by: Zlatko Kirovakov, et al.
Published: (2025-02-01)

DPPH Scavenging Activity, Reducing Power, and Metal Chelating Capacity of Compound 1-(2,5-dihydroxyphenyl)-3-pyridine-2-yl-propenone
by: Navista Sri Octa Ujiantari, et al.
Published: (2023-12-01)

Effects of the dynamics of noise-induced calcium signals in a biophysical model of the astrocytic process
by: Ermolaeva, Anastasia Viktorovna, et al.
Published: (2025-01-01)

Capitalismo con características chinas. Conceptos y desarrollo en la tercera década del siglo XXI
by: Enrique Dussel Peters
Published: (2022-01-01)

Actualities in the phytochemical research on selected terpenes
by: Jerković Igor, et al.
Published: (2019-12-01)

Preparation and Study Annealing Effect on Structure and Optical Properties of ZnIn2(Se0.8Te0.2)4 Thin Film
by: Bushra H. Hussein, et al.
Published: (2025-01-01)

Free fatty acid receptor 2 promotes cardiomyocyte hypertrophy by activating STAT3 and GATA4
by: Hui Gao, et al.
Published: (2022-03-01)

Improving anticorrosive properties of coatings based on zinc alloy TsAMSv4-1-2,5 doped with strontium
by: I. N. Ganiev, et al.
Published: (2020-06-01)

Nicotine promotes M2 macrophage polarization through α5-nAChR/SOX2/CSF-1 axis in lung adenocarcinoma
by: Guiyu Kang, et al.
Published: (2024-11-01)

Sciatic nerve analysis in thyroid hormone transporters Mct8 and Oatp1c1 knockout mice
by: Steffen Mayerl, et al.
Published: (2025-02-01)

Long noncoding RNA DHRS4 antisense RNA 1 suppresses osteosarcoma cell proliferation and promotes apoptosis through a competitive endogenous RNA mechanism
by: Zhouzhou Tang, et al.
Published: (2025-01-01)

In vitro antitumor and immunomodulatory activities of 1,2,4-oxadiazole derivatives
by: Héverton Mendes Araújo, et al.
Published: (2025-03-01)

4-Hydroxycinnamic acid attenuates neuronal cell death by inducing expression of plasma membrane redox enzymes and improving mitochondrial functions
by: Sujin Park, et al.
Published: (2023-07-01)

Antimicrobial and Antibiofilm Activity of 4-Benzylidene-2-methyl-oxazoline-5-one against Pathogen Bacteria
by: Zahra Mortazavi, et al.
Published: (2024-02-01)

Influence of Secondary Inorganic Aerosol on the Concentrations of PM2.5 and PM0.1 during Air Pollution Episodes in Hanoi, Vietnam
by: Nguyen-Quoc Dat, et al.
Published: (2024-02-01)

Enhancing laboratory education through collaborative online international learning: A case study between USA and UK students
by: Matthew Allan Jones, et al.
Published: (2025-01-01)

A comprehensive DFT/TDDFT investigation into the influence of electron acceptors on the photophysical properties of ullazine-based D-π-A-π-A photosensitizers
by: Jing Huang, et al.
Published: (2025-01-01)