Co(II) Complex of Mefloquine Hydrochloride: Synthesis, Antimicrobial Potential, Antimalaria and Toxicological Activities

Co(II) Complex of Mefloquine Hydrochloride: Synthesis, Antimicrobial Potential, Antimalaria and Toxicological Activities

Transition metal complex of Co(II) with Mefloquine hydrochloride (antimalaria drug) was synthesized using template method. Chemical analysis including conductivity measurements and spectroscopic studies were used to propose the geometry and mode of binding of the ligand to metal ion. From analytical...

Full description

Saved in:

Bibliographic Details
Main Authors:	Adediji J. Femi, Obaleye J. Ayoola
Format:	Article
Language:	English
Published:	Wiley 2012-01-01
Series:	E-Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2012/940258
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Synthesis and antiplasmodial evaluation of novel mefloquine-based fumardiamides
by: Beus Maja, et al.
Published: (2019-06-01)

Mefloquine Dangers – Fact or Fancy?
by: JS Keystone, et al.
Published: (1995-01-01)

Synthesis, antiproliferative and antiplasmodial evaluation of new chloroquine and mefloquine-based harmiquins
by: Pavić Kristina, et al.
Published: (2023-12-01)

Synthesis, Characterization and Antimicrobial Activity of Mixed Schiff Base Ligand Complexes of Co(II), Ni(II), Cu(II) and Zn(II)
by: A. K. Mapari, et al.
Published: (2011-01-01)

Synthesis, DFT Calculation, and Antimicrobial Studies of Novel Zn(II), Co(II), Cu(II), and Mn(II) Heteroleptic Complexes Containing Benzoylacetone and Dithiocarbamate
by: Anthony C. Ekennia, et al.
Published: (2015-01-01)

Microwave Synthesis, Spectral, Thermal and Antimicrobial Studies of Some Co(II), Ni(II) and Cu(II) Complexes Containing 2-Aminothiazole Moiety
by: A. P. Mishra, et al.
Published: (2012-01-01)

Antimalaria Effect of the Ethanolic Stem Bark Extracts of Ficus platyphylla Del
by: Isma'il Shittu, et al.
Published: (2011-01-01)

Novel Zinc(II) Complexes of Heterocyclic Ligands as Antimicrobial Agents: Synthesis, Characterisation, and Antimicrobial Studies
by: Ramesh S. Yamgar, et al.
Published: (2014-01-01)

Synthesis, Characterization, and Evaluation of Antimicrobial and Antifertility Efficacy of Heterobimetallic Complexes of Copper (II)
by: Ashu Chaudhary, et al.
Published: (2017-01-01)

Synthesis, Characterization and Antibacterial activity of Benzimidazole Derivatives and their Cu (ii),Ni (ii) and Co (ii) complexes
by: Haftom Welderufael, et al.
Published: (2023-04-01)

Synthesis, Characterization and Antibacterial activity of Benzimidazole Derivatives and their Cu (ii),Ni (ii) and Co (ii) complexes
by: Haftom Welderufael, et al.
Published: (2023-04-01)

Synthesis, Characterization, and Antimicrobial Activity Studies of Ni(II) Complex with Pyridine as a Ligand
by: Faridul Islam, et al.
Published: (2015-01-01)

Co(II) and Cd(II) Complexes Derived from Heterocyclic Schiff-Bases: Synthesis, Structural Characterisation, and Biological Activity
by: Riyadh M. Ahmed, et al.
Published: (2013-01-01)

Toxicological complexity of microplastics in terrestrial ecosystems
by: Fazal Ullah, et al.
Published: (2025-02-01)

SN-Donor Methylthioanilines and Copper(II) Complexes: Synthesis, Spectral Properties, and In Vitro Antimicrobial Activity
by: Temitope E. Olalekan, et al.
Published: (2019-01-01)

Transition Metal(II) Complexes with Cefotaxime-Derived Schiff Base: Synthesis, Characterization, and Antimicrobial Studies
by: Aurora Reiss, et al.
Published: (2014-01-01)

Synthesis, Crystal Structure, Spectroscopic Properties, and Interaction with Ct-DNA of Zn(II) with 2-Aminoethanethiol Hydrochloride Ligand
by: Xu-gang Shu, et al.
Published: (2016-01-01)

Synthesis, Crystal Structures, and Antimicrobial and Antitumor Studies of Two Zinc(II) Complexes with Pyridine Thiazole Derivatives
by: Zou Xun-Zhong, et al.
Published: (2020-01-01)

Novel FeII and CoII Complexes of Natural Product Tryptanthrin: Synthesis and Binding with G-Quadruplex DNA
by: Yi-ning Zhong, et al.
Published: (2016-01-01)

Preparation and Antimicrobial Screeningof Cu (II), Ni (II), Zn (II) Cd (II) Complexes
by: R. M. Desai, et al.
Published: (2006-01-01)

A Pharmacological and Toxicological Profile of Silver as an Antimicrobial Agent in Medical Devices
by: Alan B. G. Lansdown
Published: (2010-01-01)

Syntheses, Characterization, and Antimicrobial Screening of N-(benzothiazol-2-yl)benzenesulphonamide and its Cu(I), Ni(II), Mn(II), Co(II), and Zn(II) Complexes
by: N. L. Obasi, et al.
Published: (2012-01-01)

Synthesis and Characterization of New Schiff Bases Derived from N (1)-Substituted Isatin with Dithiooxamide and Their Co(II), Ni(II), Cu(II), Pd(II), and Pt(IV) Complexes
by: Ahlam J. Abdul-Ghani, et al.
Published: (2009-01-01)

Synthesis and Characterization of 2-(Hydroxyimino)-1-(phenylpropylidene)thiocarbonohydrazide and its Metal Complexes with Co(II), Ni(II) and Cu(II) Ions
by: A. Venkatchallam, et al.
Published: (2009-01-01)

Ni(II), Cu(II), Mn(II), and Fe(II) Metal Complexes Containing 1,3-Bis(diphenylphosphino)propane and Pyridine Derivative: Synthesis, Characterization, and Antimicrobial Activity
by: Maged S. Al-Fakeh, et al.
Published: (2021-01-01)

Synthesis, Characterization, and Biological Activity of Mn(II), Fe(II), Co(II), Ni(II), Cu(II), Zn(II), and Cd(II) Complexes of N-Thiophenoyl-N′-Phenylthiocarbohydrazide
by: M. Yadav, et al.
Published: (2013-01-01)

QUANTITATIVE STRUCTURE–ACTIVITY RELATIONSHIPS (QSAR) STUDY ON NOVEL 4-AMIDINOQUINOLINE AND 10-AMIDINOBENZONAPHTHYRIDINE DERIVATIVES AS POTENT ANTIMALARIA AGENT
by: Aliyu Wappah Mahmud, et al.
Published: (2019-06-01)

Synthesis of Amino Acid Schiff Base Nickel (II) Complexes as Potential Anticancer Drugs In Vitro
by: Yang Li, et al.
Published: (2020-01-01)

Metal-Based Antibacterial and Antifungal Agents: Synthesis, Characterization, and In Vitro Biological Evaluation of Co(II), Cu(II), Ni(II), and Zn(II) Complexes with Amino Acid-Derived Compounds
by: Zahid H. Chohan, et al.
Published: (2006-01-01)

Synthesis, Characterization and Antibacterial Activity of Mn(II), Co(II), Ni(II) and Cu(II) Complexes of 4-Carboxaldehyde Phenylhydrazone- 1-phenyl-3-methyl-2-pyrazolin-5-one
by: R. N. Pandya, et al.
Published: (2010-01-01)

An Efficient Approach to the Synthesis of Novel Oxazolidinones as Potential Antimicrobial Agents
by: Kavita Devi, et al.
Published: (2013-01-01)

Synthesis and Evaluation of Some Coumarin Containing Potential Antimicrobial Agents
by: Sayali D. Kudale, et al.
Published: (2012-01-01)

Synthesis and Crystal Structure Characterization of Zinc (II) Tetronic Acid Complexes
by: K. C. Prousis, et al.
Published: (2010-01-01)

Stability Indicating HPLC Method for Simultaneous Quantification of Trihexyphenidyl Hydrochloride, Trifluoperazine Hydrochloride and Chlorpromazine Hydrochloride from Tablet Formulation
by: P. Shetti, et al.
Published: (2010-01-01)

Clinical considerations on antimicrobial resistance potential of complex microbiological samples
by: Norbert Solymosi, et al.
Published: (2025-01-01)

Synthesis, characterization and antimicrobial effect of Cu(ii) and Zn(ii) compounds derived from 1,2,4-triazoles
by: Patricia Saraiva Vilas Boas de Almeida, et al.
Published: (2022-01-01)

Cr(III),Mn(II),Fe(III),Co(II),Ni(II),Cu(II) and Zn(II) Complexes with Diisobutyldithiocarbamato Ligand
by: Mohammad Tarique
Published: (2011-01-01)

Synthesis and Oxidation ofCobalt(II) Pheophytin-α Complex
by: Ezekiel D. Dikio, et al.
Published: (2011-01-01)

Synthesis and Cytotoxic Evaluation of Steroidal Copper (Cu (II)) Complexes
by: Yanmin Huang, et al.
Published: (2017-01-01)

Assessment of food toxicology
by: Alexander Gosslau
Published: (2016-09-01)