Value of combining lung ultrasound score with oxygenation and functional indices in determining weaning timing for critically ill pediatric patients
Abstract Objective This study aims to investigate the predictive effectiveness of bedside lung ultrasound score (LUS) in conjunction with rapid shallow breathing index (RSBI) and oxygenation index (P/F ratio) for weaning pediatric patients from mechanical ventilation. Methods This was a retrospectiv...
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2025-01-01
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| author | Ximeng Hao Hongnian Duan Qiushuang Li Dan Wang Xin Yin Zhiyan Di Shanshan Du |
| author_facet | Ximeng Hao Hongnian Duan Qiushuang Li Dan Wang Xin Yin Zhiyan Di Shanshan Du |
| author_sort | Ximeng Hao |
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| description | Abstract Objective This study aims to investigate the predictive effectiveness of bedside lung ultrasound score (LUS) in conjunction with rapid shallow breathing index (RSBI) and oxygenation index (P/F ratio) for weaning pediatric patients from mechanical ventilation. Methods This was a retrospective study. Eighty-two critically ill pediatric patients, who were admitted to the Pediatric Intensive Care Unit (PICU) and underwent mechanical ventilation from January 2023 to April 2024, were enrolled in this study. Prior to weaning, all patients underwent bedside LUS, with concurrent measurements of their RSBI and P/F ratio. Patients were followed up for weaning outcomes and categorized into successful and failed weaning groups based on these outcomes. Differences in clinical baseline data, LUS scores, RSBI and P/F ratios between the two groups were compared. The predictive value of LUS scores, RSBI and P/F ratios for weaning outcomes was assessed using receiver operating characteristic (ROC) curves and the area under the curve (AUC). Results Out of the 82 subjects, 73 (89.02%) successfully weaned, while 9 (10.98%) failed. No statistically significant differences were observed in age, gender, BMI, and respiratory failure-related comorbidities between the successful and failed weaning groups (P > 0.05). Compared to the successful weaning group, the failed weaning group exhibited longer hospital and intubation durations, higher LUS and RSBI, and lower P/F ratios, with statistically significant differences (P < 0.05). An LUS score ≥ 15.5 was identified as the optimal cutoff for predicting weaning failure, with superior predictive power compared to RSBI and P/F ratios. The combined use of LUS, RSBI and P/F ratios for predicting weaning outcomes yielded a larger area under the curve, indicating higher predictive efficacy. Conclusion The LUS demonstrates a high predictive value for the weaning outcomes of pediatric patients on mechanical ventilation. |
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| institution | Kabale University |
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| language | English |
| publishDate | 2025-01-01 |
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| spelling | doaj-art-c72d474636844a87bbfc4b8a5f2b66852025-01-19T12:43:26ZengBMCBMC Medical Imaging1471-23422025-01-012511710.1186/s12880-025-01552-0Value of combining lung ultrasound score with oxygenation and functional indices in determining weaning timing for critically ill pediatric patientsXimeng Hao0Hongnian Duan1Qiushuang Li2Dan Wang3Xin Yin4Zhiyan Di5Shanshan Du6Department of Critical Care Medicine, Baoding Hospital, Beijing Children’s Hospital, Capital Medical UniversityDepartment of Critical Care Medicine, Baoding Hospital, Beijing Children’s Hospital, Capital Medical UniversityDepartment of Critical Care Medicine, Baoding Hospital, Beijing Children’s Hospital, Capital Medical UniversityDepartment of Critical Care Medicine, Baoding Hospital, Beijing Children’s Hospital, Capital Medical UniversityDepartment of Critical Care Medicine, Baoding Hospital, Beijing Children’s Hospital, Capital Medical UniversityDepartment of Ultrasound, Baoding Hospital, Beijing Children’s Hospital Affiliated to Capital Medical UniversityDepartment of Critical Care Medicine, Baoding Hospital, Beijing Children’s Hospital, Capital Medical UniversityAbstract Objective This study aims to investigate the predictive effectiveness of bedside lung ultrasound score (LUS) in conjunction with rapid shallow breathing index (RSBI) and oxygenation index (P/F ratio) for weaning pediatric patients from mechanical ventilation. Methods This was a retrospective study. Eighty-two critically ill pediatric patients, who were admitted to the Pediatric Intensive Care Unit (PICU) and underwent mechanical ventilation from January 2023 to April 2024, were enrolled in this study. Prior to weaning, all patients underwent bedside LUS, with concurrent measurements of their RSBI and P/F ratio. Patients were followed up for weaning outcomes and categorized into successful and failed weaning groups based on these outcomes. Differences in clinical baseline data, LUS scores, RSBI and P/F ratios between the two groups were compared. The predictive value of LUS scores, RSBI and P/F ratios for weaning outcomes was assessed using receiver operating characteristic (ROC) curves and the area under the curve (AUC). Results Out of the 82 subjects, 73 (89.02%) successfully weaned, while 9 (10.98%) failed. No statistically significant differences were observed in age, gender, BMI, and respiratory failure-related comorbidities between the successful and failed weaning groups (P > 0.05). Compared to the successful weaning group, the failed weaning group exhibited longer hospital and intubation durations, higher LUS and RSBI, and lower P/F ratios, with statistically significant differences (P < 0.05). An LUS score ≥ 15.5 was identified as the optimal cutoff for predicting weaning failure, with superior predictive power compared to RSBI and P/F ratios. The combined use of LUS, RSBI and P/F ratios for predicting weaning outcomes yielded a larger area under the curve, indicating higher predictive efficacy. Conclusion The LUS demonstrates a high predictive value for the weaning outcomes of pediatric patients on mechanical ventilation.https://doi.org/10.1186/s12880-025-01552-0Lung ultrasound scoreMechanical ventilationWeaningRapid shallow breathing indexOxygenation index |
| spellingShingle | Ximeng Hao Hongnian Duan Qiushuang Li Dan Wang Xin Yin Zhiyan Di Shanshan Du Value of combining lung ultrasound score with oxygenation and functional indices in determining weaning timing for critically ill pediatric patients BMC Medical Imaging Lung ultrasound score Mechanical ventilation Weaning Rapid shallow breathing index Oxygenation index |
| title | Value of combining lung ultrasound score with oxygenation and functional indices in determining weaning timing for critically ill pediatric patients |
| title_full | Value of combining lung ultrasound score with oxygenation and functional indices in determining weaning timing for critically ill pediatric patients |
| title_fullStr | Value of combining lung ultrasound score with oxygenation and functional indices in determining weaning timing for critically ill pediatric patients |
| title_full_unstemmed | Value of combining lung ultrasound score with oxygenation and functional indices in determining weaning timing for critically ill pediatric patients |
| title_short | Value of combining lung ultrasound score with oxygenation and functional indices in determining weaning timing for critically ill pediatric patients |
| title_sort | value of combining lung ultrasound score with oxygenation and functional indices in determining weaning timing for critically ill pediatric patients |
| topic | Lung ultrasound score Mechanical ventilation Weaning Rapid shallow breathing index Oxygenation index |
| url | https://doi.org/10.1186/s12880-025-01552-0 |
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