Neurofeedback self-regulating training in patients with Post traumatic stress disorder: A randomized controlled trial study protocol
Background: Post-traumatic stress disorder (PTSD) has become an important public health problem. However, the conventional therapeutic strategy, including pharmacotherapy and cognitive behavioral therapy, has limitations. Neurofeedback is a technique that utilizes electroencephalography (EEG) signal...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-12-01
|
| Series: | Integrative Medicine Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213422020300962 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849724938187964416 |
|---|---|
| author | Jungtae Leem Moon Joo Cheong Sang-hoon Yoon Hyunho Kim Hee-Geun Jo Hyeryun Lee Jeesu Kim Hyang Yi Kim Geun-Woo Kim Hyung Won Kang |
| author_facet | Jungtae Leem Moon Joo Cheong Sang-hoon Yoon Hyunho Kim Hee-Geun Jo Hyeryun Lee Jeesu Kim Hyang Yi Kim Geun-Woo Kim Hyung Won Kang |
| author_sort | Jungtae Leem |
| collection | DOAJ |
| description | Background: Post-traumatic stress disorder (PTSD) has become an important public health problem. However, the conventional therapeutic strategy, including pharmacotherapy and cognitive behavioral therapy, has limitations. Neurofeedback is a technique that utilizes electroencephalography (EEG) signaling to monitor human physiological functions and is widely used to treat patients with PTSD. The purpose of our study is to assess the efficacy and safety level of neurofeedback treatment in patients with PTSD using quantitative EEG. Methods: This is a randomized, waitlist-controlled, assessor-blinded, clinical trial. Forty-six patients with PTSD will be randomly assigned at a 1:1 ratio into two groups. The participants in the treatment group will receive neurofeedback treatment for 50 min, twice a week, for 8 weeks (16 sessions). Quantitative EEG will be utilized to monitor the physiological functions and brain waves of the participants. A four-week follow-up period is planned. The participants in the control group will wait for 12 weeks. The primary outcome is the Korean version of PTSD Checklist-5 (PCL-5-K) score. The PCL-5-K scores on week 8 will be compared between the two groups. Anxiety, depression, insomnia, emotions, EEG, quality-of-life, and safety level will be assessed as secondary outcomes. Discussion: This trial will describe a clinical research methodology for neurofeedback in patients with PTSD. The numerous subjective and objective secondary outcomes add to the value of this trial’s results. It will also suggest a therapeutic strategy for utilizing quantitative EEG in patients with PTSD. Our trial will provide basic evidence for the management of PTSD via an integrative treatment. Trial registration: Clinical Research Information Service (CRIS): KCT0003271. |
| format | Article |
| id | doaj-art-c72010c705ee4673b5c595fbad45f70c |
| institution | DOAJ |
| issn | 2213-4220 |
| language | English |
| publishDate | 2020-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Integrative Medicine Research |
| spelling | doaj-art-c72010c705ee4673b5c595fbad45f70c2025-08-20T03:10:36ZengElsevierIntegrative Medicine Research2213-42202020-12-019410046410.1016/j.imr.2020.100464Neurofeedback self-regulating training in patients with Post traumatic stress disorder: A randomized controlled trial study protocolJungtae Leem0Moon Joo Cheong1Sang-hoon Yoon2Hyunho Kim3Hee-Geun Jo4Hyeryun Lee5Jeesu Kim6Hyang Yi Kim7Geun-Woo Kim8Hyung Won Kang9Research and Development Institute, CY Pharma Co., Seoul, South Korea; Chung-Yeon Central Institute, Gwangju, South KoreaCollege of Education, Hanyang University, Seoul, South KoreaChung-Yeon Central Institute, Gwangju, South KoreaChung-Yeon Central Institute, Gwangju, South KoreaChung-Yeon Central Institute, Gwangju, South Korea; Chung-Yeon Korean Medicine Hospital, Gwangju, South KoreaDepartment of Korean Neuropsychiatry Medicine, Wonkwang University, Iksan, South KoreaDepartment of Korean Neuropsychiatry Medicine, Wonkwang University, Iksan, South KoreaDepartment of Nursing, Kyung-In Women's University, Incheon, South KoreaDepartment of Neuropsychiatry, Dongguk University Bundang Oriental Hospital, Seongnam, South Korea; Corresponding authors at: Department of Korean Neuropsychiatry Medicine, Wonkwang University, 460 Iksan-daero, Iksan-si, Jeollabuk-do, 54538, South KoreaDepartment of Korean Neuropsychiatry Medicine, Wonkwang University, Iksan, South Korea; Corresponding authors at: Department of Neuropsychiatry, Dongguk University Bundang Oriental Hospital, 268 Buljeong-ro, Bundang-gu, Seongnamsi, Gyeonggi-do, 13601, Republic of KoreaBackground: Post-traumatic stress disorder (PTSD) has become an important public health problem. However, the conventional therapeutic strategy, including pharmacotherapy and cognitive behavioral therapy, has limitations. Neurofeedback is a technique that utilizes electroencephalography (EEG) signaling to monitor human physiological functions and is widely used to treat patients with PTSD. The purpose of our study is to assess the efficacy and safety level of neurofeedback treatment in patients with PTSD using quantitative EEG. Methods: This is a randomized, waitlist-controlled, assessor-blinded, clinical trial. Forty-six patients with PTSD will be randomly assigned at a 1:1 ratio into two groups. The participants in the treatment group will receive neurofeedback treatment for 50 min, twice a week, for 8 weeks (16 sessions). Quantitative EEG will be utilized to monitor the physiological functions and brain waves of the participants. A four-week follow-up period is planned. The participants in the control group will wait for 12 weeks. The primary outcome is the Korean version of PTSD Checklist-5 (PCL-5-K) score. The PCL-5-K scores on week 8 will be compared between the two groups. Anxiety, depression, insomnia, emotions, EEG, quality-of-life, and safety level will be assessed as secondary outcomes. Discussion: This trial will describe a clinical research methodology for neurofeedback in patients with PTSD. The numerous subjective and objective secondary outcomes add to the value of this trial’s results. It will also suggest a therapeutic strategy for utilizing quantitative EEG in patients with PTSD. Our trial will provide basic evidence for the management of PTSD via an integrative treatment. Trial registration: Clinical Research Information Service (CRIS): KCT0003271.http://www.sciencedirect.com/science/article/pii/S2213422020300962Randomized controlled trialProtocolNeurofeedbackPost traumatic stress disorderQuantitative electroencephalography |
| spellingShingle | Jungtae Leem Moon Joo Cheong Sang-hoon Yoon Hyunho Kim Hee-Geun Jo Hyeryun Lee Jeesu Kim Hyang Yi Kim Geun-Woo Kim Hyung Won Kang Neurofeedback self-regulating training in patients with Post traumatic stress disorder: A randomized controlled trial study protocol Integrative Medicine Research Randomized controlled trial Protocol Neurofeedback Post traumatic stress disorder Quantitative electroencephalography |
| title | Neurofeedback self-regulating training in patients with Post traumatic stress disorder: A randomized controlled trial study protocol |
| title_full | Neurofeedback self-regulating training in patients with Post traumatic stress disorder: A randomized controlled trial study protocol |
| title_fullStr | Neurofeedback self-regulating training in patients with Post traumatic stress disorder: A randomized controlled trial study protocol |
| title_full_unstemmed | Neurofeedback self-regulating training in patients with Post traumatic stress disorder: A randomized controlled trial study protocol |
| title_short | Neurofeedback self-regulating training in patients with Post traumatic stress disorder: A randomized controlled trial study protocol |
| title_sort | neurofeedback self regulating training in patients with post traumatic stress disorder a randomized controlled trial study protocol |
| topic | Randomized controlled trial Protocol Neurofeedback Post traumatic stress disorder Quantitative electroencephalography |
| url | http://www.sciencedirect.com/science/article/pii/S2213422020300962 |
| work_keys_str_mv | AT jungtaeleem neurofeedbackselfregulatingtraininginpatientswithposttraumaticstressdisorderarandomizedcontrolledtrialstudyprotocol AT moonjoocheong neurofeedbackselfregulatingtraininginpatientswithposttraumaticstressdisorderarandomizedcontrolledtrialstudyprotocol AT sanghoonyoon neurofeedbackselfregulatingtraininginpatientswithposttraumaticstressdisorderarandomizedcontrolledtrialstudyprotocol AT hyunhokim neurofeedbackselfregulatingtraininginpatientswithposttraumaticstressdisorderarandomizedcontrolledtrialstudyprotocol AT heegeunjo neurofeedbackselfregulatingtraininginpatientswithposttraumaticstressdisorderarandomizedcontrolledtrialstudyprotocol AT hyeryunlee neurofeedbackselfregulatingtraininginpatientswithposttraumaticstressdisorderarandomizedcontrolledtrialstudyprotocol AT jeesukim neurofeedbackselfregulatingtraininginpatientswithposttraumaticstressdisorderarandomizedcontrolledtrialstudyprotocol AT hyangyikim neurofeedbackselfregulatingtraininginpatientswithposttraumaticstressdisorderarandomizedcontrolledtrialstudyprotocol AT geunwookim neurofeedbackselfregulatingtraininginpatientswithposttraumaticstressdisorderarandomizedcontrolledtrialstudyprotocol AT hyungwonkang neurofeedbackselfregulatingtraininginpatientswithposttraumaticstressdisorderarandomizedcontrolledtrialstudyprotocol |