Microbial Transformations of 7-Hydroxyflavanone

Microbial transformations of racemic 7-hydroxyflavanone using strains of genus Aspergillus (A. niger KB, A. niger 13/5, A. ochraceus 456) and the species Penicillium chermesinum 113 were studied. The products of O-methylation, O-methylation along with hydroxylation at C-3′ and C-4′, reduction of the...

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Main Authors: Edyta Kostrzewa-Susłow, Tomasz Janeczko
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/2012/254929
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author Edyta Kostrzewa-Susłow
Tomasz Janeczko
author_facet Edyta Kostrzewa-Susłow
Tomasz Janeczko
author_sort Edyta Kostrzewa-Susłow
collection DOAJ
description Microbial transformations of racemic 7-hydroxyflavanone using strains of genus Aspergillus (A. niger KB, A. niger 13/5, A. ochraceus 456) and the species Penicillium chermesinum 113 were studied. The products of O-methylation, O-methylation along with hydroxylation at C-3′ and C-4′, reduction of the carbonyl group, reduction of the carbonyl group along with hydroxylation at C-5, and dehydrogenation of C-2 and C-3 were obtained. Most of the products (with the exception of the O-methylation one) have stronger antioxidant properties than the initial substrate.
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series The Scientific World Journal
spelling doaj-art-c717dca0e2c946e6bdc5696e85797c392025-02-03T01:21:06ZengWileyThe Scientific World Journal1537-744X2012-01-01201210.1100/2012/254929254929Microbial Transformations of 7-HydroxyflavanoneEdyta Kostrzewa-Susłow0Tomasz Janeczko1Department of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, PolandDepartment of Chemistry, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, PolandMicrobial transformations of racemic 7-hydroxyflavanone using strains of genus Aspergillus (A. niger KB, A. niger 13/5, A. ochraceus 456) and the species Penicillium chermesinum 113 were studied. The products of O-methylation, O-methylation along with hydroxylation at C-3′ and C-4′, reduction of the carbonyl group, reduction of the carbonyl group along with hydroxylation at C-5, and dehydrogenation of C-2 and C-3 were obtained. Most of the products (with the exception of the O-methylation one) have stronger antioxidant properties than the initial substrate.http://dx.doi.org/10.1100/2012/254929
spellingShingle Edyta Kostrzewa-Susłow
Tomasz Janeczko
Microbial Transformations of 7-Hydroxyflavanone
The Scientific World Journal
title Microbial Transformations of 7-Hydroxyflavanone
title_full Microbial Transformations of 7-Hydroxyflavanone
title_fullStr Microbial Transformations of 7-Hydroxyflavanone
title_full_unstemmed Microbial Transformations of 7-Hydroxyflavanone
title_short Microbial Transformations of 7-Hydroxyflavanone
title_sort microbial transformations of 7 hydroxyflavanone
url http://dx.doi.org/10.1100/2012/254929
work_keys_str_mv AT edytakostrzewasusłow microbialtransformationsof7hydroxyflavanone
AT tomaszjaneczko microbialtransformationsof7hydroxyflavanone