Pulmonary Alveolar Microlithiasis and Rheumatoid Arthritis: A Case Report and Review of the Literature
Pulmonary alveolar microlithiasis is a rare autosomal recessive condition that is characterized by the formation of excessive calcium phosphate microliths in the alveoli. Most patients are diagnosed in adulthood due to the slow progression of the disease. Children with this disease are asymptomatic,...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2021/8811507 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832547668389265408 |
|---|---|
| author | Waleed Hafiz Ahmedhusam Alahmed Mohammed Alahmadi Rakan Alotaibi Abdullah Alsharif Safwan Alim Mohammed Mokhtar Kholoud Al-Maabdi Omaima Badr |
| author_facet | Waleed Hafiz Ahmedhusam Alahmed Mohammed Alahmadi Rakan Alotaibi Abdullah Alsharif Safwan Alim Mohammed Mokhtar Kholoud Al-Maabdi Omaima Badr |
| author_sort | Waleed Hafiz |
| collection | DOAJ |
| description | Pulmonary alveolar microlithiasis is a rare autosomal recessive condition that is characterized by the formation of excessive calcium phosphate microliths in the alveoli. Most patients are diagnosed in adulthood due to the slow progression of the disease. Children with this disease are asymptomatic, and changes in the lung parenchyma are usually discovered incidentally. The diagnosis is made by the combination of a positive chest imaging and histological examination. Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by chronic seropositive symmetrical inflammatory polyarthritis with numerous extra-articular manifestations. It targets the lining of the synovial membranes, frequently affects females more than males, and is treated with the disease-modifying antirheumatic drugs (DMARDs). If left untreated, it leads to increased morbidity, mortality, and socioeconomic burdens. In this case, we report a 19-year-old young man who presented with clinical and radiographic features of PAM associated with RA. |
| format | Article |
| id | doaj-art-c70fed6c4f84405eaf886ebe15587a8b |
| institution | Kabale University |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-c70fed6c4f84405eaf886ebe15587a8b2025-02-03T06:43:58ZengWileyCase Reports in Rheumatology2090-68892090-68972021-01-01202110.1155/2021/88115078811507Pulmonary Alveolar Microlithiasis and Rheumatoid Arthritis: A Case Report and Review of the LiteratureWaleed Hafiz0Ahmedhusam Alahmed1Mohammed Alahmadi2Rakan Alotaibi3Abdullah Alsharif4Safwan Alim5Mohammed Mokhtar6Kholoud Al-Maabdi7Omaima Badr8Department of Medicine, College of Medicine, Umm Al-Qura University, Makkah, Saudi ArabiaDepartment of Medicine, Alnoor Specialist Hospital, Makkah, Saudi ArabiaDepartment of Medicine, College of Medicine, Umm Al-Qura University, Makkah, Saudi ArabiaDepartment of Medicine, College of Medicine, Umm Al-Qura University, Makkah, Saudi ArabiaDepartment of Medicine, College of Medicine, Umm Al-Qura University, Makkah, Saudi ArabiaDepartment of Medicine, College of Medicine, Umm Al-Qura University, Makkah, Saudi ArabiaDepartment of Medicine, College of Medicine, Umm Al-Qura University, Makkah, Saudi ArabiaDepartment of Medicine, East Jeddah Hospital, Jeddah, Saudi ArabiaDepartment of Medicine, Alnoor Specialist Hospital, Makkah, Saudi ArabiaPulmonary alveolar microlithiasis is a rare autosomal recessive condition that is characterized by the formation of excessive calcium phosphate microliths in the alveoli. Most patients are diagnosed in adulthood due to the slow progression of the disease. Children with this disease are asymptomatic, and changes in the lung parenchyma are usually discovered incidentally. The diagnosis is made by the combination of a positive chest imaging and histological examination. Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by chronic seropositive symmetrical inflammatory polyarthritis with numerous extra-articular manifestations. It targets the lining of the synovial membranes, frequently affects females more than males, and is treated with the disease-modifying antirheumatic drugs (DMARDs). If left untreated, it leads to increased morbidity, mortality, and socioeconomic burdens. In this case, we report a 19-year-old young man who presented with clinical and radiographic features of PAM associated with RA.http://dx.doi.org/10.1155/2021/8811507 |
| spellingShingle | Waleed Hafiz Ahmedhusam Alahmed Mohammed Alahmadi Rakan Alotaibi Abdullah Alsharif Safwan Alim Mohammed Mokhtar Kholoud Al-Maabdi Omaima Badr Pulmonary Alveolar Microlithiasis and Rheumatoid Arthritis: A Case Report and Review of the Literature Case Reports in Rheumatology |
| title | Pulmonary Alveolar Microlithiasis and Rheumatoid Arthritis: A Case Report and Review of the Literature |
| title_full | Pulmonary Alveolar Microlithiasis and Rheumatoid Arthritis: A Case Report and Review of the Literature |
| title_fullStr | Pulmonary Alveolar Microlithiasis and Rheumatoid Arthritis: A Case Report and Review of the Literature |
| title_full_unstemmed | Pulmonary Alveolar Microlithiasis and Rheumatoid Arthritis: A Case Report and Review of the Literature |
| title_short | Pulmonary Alveolar Microlithiasis and Rheumatoid Arthritis: A Case Report and Review of the Literature |
| title_sort | pulmonary alveolar microlithiasis and rheumatoid arthritis a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2021/8811507 |
| work_keys_str_mv | AT waleedhafiz pulmonaryalveolarmicrolithiasisandrheumatoidarthritisacasereportandreviewoftheliterature AT ahmedhusamalahmed pulmonaryalveolarmicrolithiasisandrheumatoidarthritisacasereportandreviewoftheliterature AT mohammedalahmadi pulmonaryalveolarmicrolithiasisandrheumatoidarthritisacasereportandreviewoftheliterature AT rakanalotaibi pulmonaryalveolarmicrolithiasisandrheumatoidarthritisacasereportandreviewoftheliterature AT abdullahalsharif pulmonaryalveolarmicrolithiasisandrheumatoidarthritisacasereportandreviewoftheliterature AT safwanalim pulmonaryalveolarmicrolithiasisandrheumatoidarthritisacasereportandreviewoftheliterature AT mohammedmokhtar pulmonaryalveolarmicrolithiasisandrheumatoidarthritisacasereportandreviewoftheliterature AT kholoudalmaabdi pulmonaryalveolarmicrolithiasisandrheumatoidarthritisacasereportandreviewoftheliterature AT omaimabadr pulmonaryalveolarmicrolithiasisandrheumatoidarthritisacasereportandreviewoftheliterature |